Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5850504 | 0.81 | LMNA (0.43) | LMNANPSR1L3MBTL1GAATSHR | |
| SCHEMBL11099557 | 0.78 | HCRTR1 (0.56) | HCRTR1LMNANPSR1L3MBTL1POLB | |
| SCHEMBL30729242 | 0.75 | HCRTR1 (0.53) | HCRTR1LMNANPSR1L3MBTL1POLB | |
| SCHEMBL5850884 | 0.74 | SRC (0.47) | LMNAL3MBTL1GAATP53 | |
| SCHEMBL23163313 | 0.74 | HCRTR1 (0.59) | HCRTR1LMNANPSR1L3MBTL1POLB | |
| SCHEMBL28661384 | 0.73 | LMNA (0.44) | HCRTR1LMNAL3MBTL1MTNR1AMTNR1B | |
| SCHEMBL28031699 | 0.72 | HCRTR1 (0.57) | HCRTR1LMNANPSR1L3MBTL1POLB | |
| SCHEMBL11763718 | 0.71 | HCRTR1 (0.56) | HCRTR1LMNANPSR1L3MBTL1IDO1 | |
| SCHEMBL28439575 | 0.71 | INPPL1 (0.58) | HCRTR1LMNAL3MBTL1GAARAB9A | |
| SCHEMBL8016743 | 0.71 | HCRTR1 (0.47) | HCRTR1LMNANPSR1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5557003-A | SOLVENT EXTRACTION OF ZINC FROM ORE | ZENECA LIMITED (GB) | 1996-09-17 | — | — | US | disclosed |