Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942210 | 0.81 | HCRTR1 (0.47) | LMNAACHEL3MBTL1NPSR1GAA | |
| SCHEMBL11556570 | 0.78 | ACHE (0.52) | LMNAHTTMAPTACHEL3MBTL1 | |
| SCHEMBL5850884 | 0.74 | SRC (0.47) | LMNAHTTL3MBTL1TDP1GAA | |
| SCHEMBL11050482 | 0.74 | MAOB (0.41) | LMNAHTTMAPTKMT2AALDH1A1 | |
| SCHEMBL29790831 | 0.74 | ALDH1A1 (0.61) | LMNAHTTMAPTACHEL3MBTL1 | |
| SCHEMBL187081 | 0.74 | ALDH1A1 (0.61) | LMNAHTTMAPTACHEL3MBTL1 | |
| SCHEMBL5486829 | 0.72 | ACHE (0.54) | LMNAHTTMAPTACHEL3MBTL1 | |
| SCHEMBL4136823 | 0.72 | ACHE (0.54) | LMNAHTTMAPTACHEL3MBTL1 | |
| SCHEMBL5850243 | 0.71 | CYP3A4 (0.53) | LMNAMAPTACHENPSR1GAA | |
| SCHEMBL3630170 | 0.71 | L3MBTL1 (0.54) | LMNAHTTMAPTACHEL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153901-B2 | Low viscosity flame retardants are the reaction product of a mixed ester of tetrabromophthalic acid with diethylene glycol and propylene glycol with an acid anhydride, organic phosphate, or organic chlorophosphate; minimizing visible scorching of the flexible polyurethane foam during its production | ALBEMARLE CORPORATION (US) | 2006-12-26 | — | — | US | disclosed |
| US-20050113495-A1 | Flame retardant, additive compositions, and flame retardant polyurethanes | ALBEMARLE CORPORATION | 2005-05-26 | — | — | US | disclosed |