Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27083890 | 0.80 | TSHR (0.67) | TSHRNPSR1POLBMAPTALDH1A1 | |
| SCHEMBL8746385 | 0.80 | TSHR (0.67) | TSHRNPSR1POLBMAPTALDH1A1 | |
| SCHEMBL8942583 | 0.79 | TSHR (0.62) | TSHRCACNA1CPOLBMAPTALDH1A1 | |
| SCHEMBL11669883 | 0.72 | CACNA1C (0.59) | TSHRCACNA1CPOLBMAPTMAPK1 | |
| SCHEMBL4420346 | 0.71 | SMN1; SMN2 (0.64) | TSHRKDM4ENPSR1POLBMAPT | |
| SCHEMBL6978503 | 0.71 | BCL9 (0.52) | TSHRKDM4EPOLBMAPTALDH1A1 | |
| SCHEMBL11829575 | 0.70 | ADORA3 (0.69) | TSHRKDM4ENPSR1CACNA1CPOLB | |
| SCHEMBL3340975 | 0.69 | NPSR1 (0.52) | KDM4ENPSR1POLBMAPTALDH1A1 | |
| SCHEMBL4271172 | 0.69 | POLB (0.51) | KDM4ENPSR1POLBMAPTALDH1A1 | |
| SCHEMBL873079 | 0.69 | TSHR (0.67) | TSHRKDM4EPOLBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5569774-A | Process for the preparation of chlorine-substituted olefins | BASF AKTIENGESELLSCHAFT (DE) | 1996-10-29 | — | — | US | disclosed |
| EP-0632799-B1 | PROCESS FOR PRODUCING CHLORINE-SUBSTITUTED OLEFINE COMPOUNDS | BASF AG (DE) | 1996-10-09 | — | — | EP | disclosed |
| EP-0632799-A1 | PROCESS FOR PRODUCING CHLORINE-SUBSTITUTED OLEFINE COMPOUNDS. | BASF AG (DE) | 1995-01-11 | — | — | EP | disclosed |
| WO-1993019034-A1 | PROCESS FOR PRODUCING CHLORINE-SUBSTITUTED OLEFINE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 1993-09-30 | — | — | WO | disclosed |