SCHEMBL8942334

SCHEMBL8942334

Cc1c([O])c(Oc2ccccc2)c(COc2ccccc2)c(C)c1Oc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 5/20 0.41
PPARG P37231 1/20 0.40
FFAR1 O14842 4/20 0.39
FFAR4 Q5NUL3 1/20 0.39
APP P05067 1/20 0.38
PLA2G2A P14555 1/20 0.38
KCNA3 P22001 1/20 0.37
KCNH2 Q12809 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8942231 0.78 LTA4H (0.42) LTA4HFFAR1
SCHEMBL8942482 0.77 LTA4H (0.46) LTA4H
SCHEMBL12129561 0.73 KCNH2 (0.50) LTA4HAPPKCNA3KCNH2
SCHEMBL13810999 0.69 LTA4H (0.55) LTA4H
SCHEMBL13622878 0.69 LMNA (0.50) APP
SCHEMBL8651083 0.67 KCNH2 (0.44) LTA4HFFAR1KCNH2
SCHEMBL1634514 0.66 KCNH2 (0.52) LTA4HAPPKCNA3KCNH2
SCHEMBL24625401 0.66 LTA4H (0.50) LTA4H
SCHEMBL11853860 0.65 FFAR1 (0.59) LTA4HPPARGFFAR1FFAR4APP
SCHEMBL11860320 0.65 MAOB (0.61) LTA4HFFAR1FFAR4PLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5557003-A SOLVENT EXTRACTION OF ZINC FROM ORE ZENECA LIMITED (GB) 1996-09-17 US disclosed