Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24401196 | 0.80 | CA14 (0.41) | CA14TDP1MEN1GAAKMT2A | |
| SCHEMBL8782986 | 0.76 | MAOA (0.50) | CA14MAOAMAOBTDP1MEN1 | |
| SCHEMBL929384 | 0.76 | HDAC6 (0.36) | CA14HDAC6CA12CA1CA7 | |
| SCHEMBL9901110 | 0.74 | CA14 (0.44) | CA14HDAC6CA12CA1CA7 | |
| SCHEMBL12286131 | 0.72 | MAOA (0.43) | CA14MAOAMAOBTDP1MEN1 | |
| SCHEMBL15049400 | 0.72 | MAOA (0.57) | MAOAMAOBTDP1MEN1GAA | |
| SCHEMBL9434997 | 0.71 | CA14 (0.43) | CA14MAOAMAOBTDP1MEN1 | |
| SCHEMBL4061706 | 0.71 | TDP1 (0.42) | CA14TDP1HDAC6CA12CA1 | |
| SCHEMBL25074829 | 0.71 | HDAC6 (0.35) | CA14HDAC6CA12CA1CA7 | |
| SCHEMBL24172307 | 0.71 | CA12 (0.39) | CA14HDAC6CA12CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |