Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | KDM4A | O75164 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.32 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8887438 | 0.81 | HDAC1 (0.40) | CA14HDAC1HDAC2HDAC6L3MBTL1 | |
| SCHEMBL9434880 | 0.81 | HDAC6 (0.44) | CA14TDP1HDAC1HDAC2HDAC6 | |
| SCHEMBL21937996 | 0.79 | CA14 (0.41) | CA14HDAC1HDAC2HDAC6L3MBTL1 | |
| SCHEMBL4061706 | 0.77 | TDP1 (0.42) | CA14TDP1HDAC1HDAC2HDAC6 | |
| SCHEMBL24172307 | 0.77 | CA12 (0.39) | CA14HDAC1HDAC2HDAC6CA12 | |
| SCHEMBL15571120 | 0.75 | CA14 (0.42) | CA14TDP1HDAC1HDAC2HDAC6 | |
| SCHEMBL24401196 | 0.75 | CA14 (0.41) | CA14TDP1HDAC1HDAC2HDAC6 | |
| SCHEMBL9435044 | 0.74 | KDM4A (0.50) | KDM4AHIF1ATET2DOHHGAA | |
| SCHEMBL19784441 | 0.73 | HDAC1 (0.44) | TDP1HDAC1HDAC2HDAC6GAA | |
| SCHEMBL1222571 | 0.72 | HDAC6 (0.36) | CA14HDAC1HDAC2HDAC6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994011367-A1 | 2-(PYRID-2'-YL)-2-THIAZOLINE-4(S)-CARBOXYLIC ACID DERIVATIVES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION INC. (US) | 1994-05-26 | — | — | WO | disclosed |