Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.35 |
| ▸ | PPARA | Q07869 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8719727 | 0.75 | ESR1 (0.50) | PPARGPPARAMAPK1SMN1; SMN2ESR1 | |
| SCHEMBL8942353 | 0.72 | LTA4H (0.36) | PPARGPPARATDP1L3MBTL1MTNR1A | |
| SCHEMBL4192650 | 0.70 | CA1 (0.40) | MAPK1ESR1TDP1CYP1A2CYP2C9 | |
| SCHEMBL11579137 | 0.66 | SCN4A (0.41) | PPARGPPARAMAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL9453500 | 0.66 | KDM4E (0.41) | MAPK1SMN1; SMN2ESR1CYP1A2CYP2C9 | |
| SCHEMBL8651083 | 0.64 | KCNH2 (0.44) | TDP1NPC1RAB9A | |
| SCHEMBL10744223 | 0.64 | SMN1; SMN2 (0.48) | MAPK1SMN1; SMN2TDP1NPC1RAB9A | |
| SCHEMBL49378 | 0.63 | — | — | |
| SCHEMBL8717190 | 0.63 | LMNA (0.42) | PPARGPPARASMN1; SMN2NPC1RAB9A | |
| SCHEMBL19757664 | 0.63 | ESR1 (0.45) | MAPK1SMN1; SMN2ESR1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5557003-A | SOLVENT EXTRACTION OF ZINC FROM ORE | ZENECA LIMITED (GB) | 1996-09-17 | — | — | US | disclosed |