Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 2/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | GCK | P35557 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942229 | 0.87 | KDM4E (0.53) | ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL8351344 | 0.83 | KDM4E (0.36) | ALDH1A1KDM4EHPGDHTT | |
| SCHEMBL8346826 | 0.82 | ADORA2A (0.32) | ALDH1A1KDM4EHPGD | |
| SCHEMBL8942328 | 0.78 | PTK2 (0.34) | BTKPTK2 | |
| SCHEMBL8942327 | 0.76 | KDM4E (0.38) | ALDH1A1KDM4EHPGDMAPTHTT | |
| SCHEMBL8942375 | 0.73 | KDM4E (0.34) | ALDH1A1KDM4EHPGDMAPTHTT | |
| SCHEMBL9602080 | 0.72 | CYP4F2 (0.42) | MAPTHTT | |
| SCHEMBL8351325 | 0.70 | KDM4E (0.50) | ALDH1A1KDM4EHPGDMAPTHTT | |
| SCHEMBL8346854 | 0.70 | PTGS1 (0.35) | ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL8942378 | 0.70 | DPP4 (0.34) | ALDH1A1KDM4EMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5302586-A | Antiischemic and -hypoxia agents, particularly after a stroke, cardiac arrest, hypoglycemia or perinatal asphxia | G. D. SEARLE & CO. (US) | 1994-04-12 | — | — | US | claimed |
| US-5482933-A | ANOXIA, ISCHEMIA | G. D. SEARLE & CO. (US) | 1996-01-09 | — | — | US | disclosed |
| US-5480876-A | FROM ANOXIA OR ISCHEMIA | G. D. SEARLE & CO. (US) | 1996-01-02 | — | — | US | disclosed |
| US-5302586-A | Antiischemic and -hypoxia agents, particularly after a stroke, cardiac arrest, hypoglycemia or perinatal asphxia | G. D. SEARLE & CO. (US) | 1994-04-12 | — | — | US | disclosed |