Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 2/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942443 | 0.88 | ALDH1A1 (0.42) | DPP4DPP8DPP9 | |
| SCHEMBL8350370 | 0.85 | DPP4 (0.31) | DPP4DPP8DPP9 | |
| SCHEMBL8349215 | 0.83 | SIRT6 (0.33) | — | |
| SCHEMBL8942458 | 0.78 | ALDH1A1 (0.38) | PTK2BTK | |
| SCHEMBL8942375 | 0.77 | KDM4E (0.34) | — | |
| SCHEMBL8942378 | 0.76 | DPP4 (0.34) | DPP4DPP8DPP9PLAU | |
| SCHEMBL8351315 | 0.73 | ALDH1A1 (0.41) | DPP4DPP8DPP9 | |
| SCHEMBL8346823 | 0.72 | TDP1 (0.33) | — | |
| SCHEMBL8346831 | 0.71 | SIRT6 (0.31) | — | |
| SCHEMBL8942184 | 0.70 | KDM4E (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5302586-A | Antiischemic and -hypoxia agents, particularly after a stroke, cardiac arrest, hypoglycemia or perinatal asphxia | G. D. SEARLE & CO. (US) | 1994-04-12 | — | — | US | claimed |
| US-5482933-A | ANOXIA, ISCHEMIA | G. D. SEARLE & CO. (US) | 1996-01-09 | — | — | US | disclosed |
| US-5302586-A | Antiischemic and -hypoxia agents, particularly after a stroke, cardiac arrest, hypoglycemia or perinatal asphxia | G. D. SEARLE & CO. (US) | 1994-04-12 | — | — | US | disclosed |