SCHEMBL8942483

SCHEMBL8942483

CNc1ccc(Nc2ccc(N)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.61
L3MBTL1 Q9Y468 4/20 0.61
ALDH1A1 P00352 4/20 0.61
ALOX12 P18054 2/20 0.61
CYP1A2 P05177 1/20 0.61
CYP3A4 P08684 1/20 0.61
CYP2C9 P11712 1/20 0.61
CYP2C19 P33261 1/20 0.61
HTT P42858 1/20 0.61
NR4A1 P22736 1/20 0.58
RAD52 P43351 1/20 0.56
HSD17B10 Q99714 3/20 0.46
APP P05067 2/20 0.46
ALOX15 P16050 2/20 0.46
KDM4E B2RXH2 2/20 0.46
TP53 P04637 1/20 0.46
HPGD P15428 1/20 0.46
SNCA P37840 1/20 0.46
BLM P54132 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22427634 1.00 MAPT (0.61) MAPTL3MBTL1ALDH1A1ALOX12CYP1A2
SCHEMBL525926 0.92
Ammonia Solution, Strong SCHEMBL11052046 0.89 TSHR (0.48) MAPTL3MBTL1ALDH1A1ALOX12CYP1A2
Hydrochloric Acid SCHEMBL1154858 0.89 TSHR (0.48) MAPTL3MBTL1ALDH1A1ALOX12CYP1A2
Hydrochloric Acid SCHEMBL6010014 0.89 TSHR (0.48) MAPTL3MBTL1ALDH1A1ALOX12CYP1A2
SCHEMBL5428343 0.86 MAPT (0.78) MAPTL3MBTL1ALDH1A1ALOX12CYP1A2
SCHEMBL29479572 0.86 MAPT (0.78) MAPTL3MBTL1ALDH1A1ALOX12CYP1A2
SCHEMBL12747008 0.86 MAPT (0.78) MAPTL3MBTL1ALDH1A1ALOX12CYP1A2
SCHEMBL18289620 0.86 MAPT (0.78) MAPTL3MBTL1ALDH1A1ALOX12CYP1A2
SCHEMBL5438258 0.86 MAPT (0.78) MAPTL3MBTL1ALDH1A1ALOX12CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023157879-A1 WEAK-ANCHORING LIQUID CRYSTAL ALIGNING AGENT, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2023-08-24 WO disclosed
WO-2023140322-A1 WEAK-ANCHORING LIQUID CRYSTAL ALIGNMENT AGENT, AND LIQUID CYRSTAL DISPLAY ELEMENT 日産化学株式会社 2023-07-27 WO disclosed
WO-2023120726-A1 WEAK-ANCHORING LIQUID CRYSTAL ALIGNMENT AGENT, AND LIQUID CYRSTAL DISPLAY ELEMENT 日産化学株式会社 2023-06-29 WO disclosed
WO-2023048278-A1 WEAKLY ANCHORING LIQUID-CRYSTAL ALIGNMENT AGENT, LIQUID-CRYSTAL DISPLAY ELEMENT, AND POLYMER 日産化学株式会社 2023-03-30 WO disclosed
WO-2022260048-A1 WEAK ANCHORING LIQUID CRYSTAL ALIGNING AGENT, LIQUID CYRSTAL DISPLAY ELEMENT AND COPOLYMER 日産化学株式会社 2022-12-15 WO disclosed
CN-114574223-A Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal element JSR株式会社 2022-06-03 CN disclosed
EP-3159737-B1 LIQUID CRYSTAL DISPLAY ELEMENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL ALIGNMENT TREATMENT AGENT NISSAN CHEMICAL CORP (JP) 2021-05-26 EP disclosed
WO-2020145175-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2020-07-16 WO disclosed
WO-2019182072-A1 POLYUREA COPOLYMER, LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME 日産化学株式会社 2019-09-26 WO disclosed
US-10023530-B2 Diamine, polyamic acid, and polyimide NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-07-17 US disclosed
US-5501927-A DISAZO OR TRISAZO DYES FUJI XEROX CO., LTD. (JP) 1996-03-26 US disclosed
US-5340929-A Inks, discoloration inhibition ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 1994-08-23 US disclosed
EP-0556741-A1 Novel trisazo dye and dye composition containing the same ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 1993-08-25 EP disclosed
US-4275184-A HYDROSILATION OF POLYDIMETHYL SILOXANE RHONE-POULENC INDUSTRIES (FR) 1981-06-23 US disclosed
US-4213914-A ADDITION-CONDENSATION COPOLYMERS RHONE-POULENC INDUSTRIES (FR) 1980-07-22 US disclosed
US-4147711-A Ethylenic silicon compounds and thermoplastic elastomers obtained therefrom RHONE-POULENC INDUSTRIES (FR) 1979-04-03 US disclosed
US-4088670-A P-(DIMETHYLVINYLSILYL-METHOXY)-BENZOYL CHLORIDE FROM DIMETHYLVINYL-CHLOROMETHYLSILANE AND A P-HYDROXYBENZOIC ACID RHONE-POULENC INDUSTRIES (FR) 1978-05-09 US disclosed
US-4057518-A Process for the manufacture of heat resistant multicellular materials RHONE-POULENC INDUSTRIES (FR) 1977-11-08 US disclosed
US-4013600-A STORAGE STABILITY RHONE-POULENC INDUSTRIES (FR) 1977-03-22 US disclosed
US-4010220-A AMINO COMPOUND, POLYURETHANE ELASTOMER RHONE-POULENC INDUSTRIES (FR) 1977-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10023530-B2 Diamine, polyamic acid, and polyimide H1-2, H1-4, H1-0 MAPT 3277/4885L3MBTL1 614/4885ALDH1A1 1921/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.