Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.46 |
| ▸ | HTR6 known ✓ | P50406 | 1/20 | 0.45 |
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B known ✓ | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C known ✓ | P18825 | 1/20 | 0.44 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6010014 | 1.00 | TSHR (0.48) | TSHRMAPTMEN1KMT2ACA12 | |
| SCHEMBL525926 | 0.97 | — | — | |
| Ammonia Solution, Strong SCHEMBL11052046 | 0.94 | TSHR (0.48) | TSHRMAPTMEN1KMT2ACA12 | |
| Benzidine SCHEMBL7896409 | 0.89 | CYP3A4 (0.58) | TSHRMAPTMEN1KMT2ACA12 | |
| SCHEMBL22427634 | 0.89 | MAPT (0.61) | TSHRMAPTMEN1KMT2ACA12 | |
| SCHEMBL8942483 | 0.89 | MAPT (0.61) | TSHRMAPTMEN1KMT2ACA12 | |
| SCHEMBL2543902 | 0.89 | CYP3A4 (0.58) | TSHRMAPTMEN1KMT2ACA12 | |
| SCHEMBL20048273 | 0.89 | CYP3A4 (0.58) | TSHRMAPTMEN1KMT2ACA12 | |
| Methane SCHEMBL29193641 | 0.87 | CYP3A4 (0.55) | TSHRMAPTMEN1KMT2ACA12 | |
| SCHEMBL7788640 | 0.87 | ACHE (0.65) | TSHRMAPTMEN1KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112853409-B | Silver-containing plating solution and preparation method of foam metal material | 哈尔滨工业大学（深圳） | 2022-07-22 | — | — | CN | claimed |
| CN-112853409-A | Silver-containing plating solution and preparation method of foam metal material | 哈尔滨工业大学（深圳） | 2021-05-28 | — | — | CN | claimed |
| CN-112853409-B | Silver-containing plating solution and preparation method of foam metal material | 哈尔滨工业大学（深圳） | 2022-07-22 | — | — | CN | disclosed |
| CN-112853409-A | Silver-containing plating solution and preparation method of foam metal material | 哈尔滨工业大学（深圳） | 2021-05-28 | — | — | CN | disclosed |
| US-10119968-B2 | Self-contained diagnostic test with advanceable test strip | TEST ANYWHERE TECHNOLOGY (US) | 2018-11-06 | — | — | US | disclosed |
| US-20180311664-A1 | APPARATUS AND METHOD FOR DETERMINING THE PRESENCE OF AN ANALYTE | TEST ANYWHERE TECHNOLOGY | 2018-11-01 | — | — | US | disclosed |
| US-20140072960-A1 | SELF DIAGNOSTIC TEST | TEST ANYWHERE TECHNOLOGY | 2014-03-13 | — | — | US | disclosed |
| WO-2013181616-A1 | SELF DIAGNOSTIC TEST | HEALTH & BLISS LLC (US) | 2013-12-05 | — | — | WO | disclosed |
| EP-1719762-B1 | NOVEL PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE (1) | EISAI R&D MAN CO LTD (JP) | 2012-06-27 | — | — | EP | disclosed |
| US-8083809-B2 | Azomethine direct dyes or reduced precursors of these dyes obtained from 2-chloro-3-amino-6-methylphenol, and hair dyeing method starting from these dyes and precursors | L'OREAL S.A. (FR) | 2011-12-27 | — | — | US | disclosed |
| EP-2229140-B1 | AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF THESE DYES OBTAINED FROM 2-CHLORO-3-AMINO-6-METHYLPHENOL, AND HAIR DYEING METHOD STARTING FROM THESE DYES AND PRECURSORS | OREAL (FR) | 2011-08-03 | — | — | EP | disclosed |
| US-5197992-A | Disazo dye, naphthol dye with triazole groups for wool, silk, polyamides and cellulose with triphenodioxazines | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-30 | — | — | US | disclosed |
| US-5196033-A | BIS-azotriazinyl reactive dyes having an N-alkyl-phenylenediamine link for cellulose textiles | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-23 | — | — | US | disclosed |
| US-5132429-A | BENZOTRIAZOLE DERIVATIVES AND FLUORESCENCE-EMITTING REAGENTS THEREOF | SHIONOGI & CO., LTD. (JP) | 1992-07-21 | — | — | US | disclosed |
| US-5059681-A | BIS-AZOTRIAZINYL REACTIVE DYES HAVING AN N-ALKYL-PHENYLENEDIAMINE LINK | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-22 | — | — | US | disclosed |
| EP-0418386-A1 | BENZOTRIAZOLE DERIVATIVES AND FLUORESCENCE-EMITTING REAGENTS CONTAINING THEM | SHIONOGI & CO., LTD. (JP) | 1991-03-27 | — | — | EP | disclosed |
| US-4021486-A | Hydroxyalkyl-amino nitrodiphenylamine compounds useful as hair dyes | CLAIROL INCORPORATED (US) | 1977-05-03 | — | — | US | disclosed |
| US-4018653-A | Instrument for the detection of Neisseria gonorrhoeae without culture | U.S. PACKAGING CORPORATION (US) | 1977-04-19 | — | — | US | disclosed |
| US-4009154-A | Process for preparing aromatic polyamides with sodium carbonate hydrate as acid acceptor | TEIJIN LIMITED (JA) | 1977-02-22 | — | — | US | disclosed |
| US-3950127-A | HAIR DYE COMPOSITIONS CONTAINING NITRODIPHENYLAMINE DYES AND METHOD FOR DYEING HAIR THEREWITH | CLAIROL INCORPORATED (US) | 1976-04-13 | — | — | US | disclosed |