Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | USP1 | O94782 | 1/20 | 0.35 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8304674 | 0.89 | GABRA5 (0.38) | MRGPRX4GABRA5KMT2ANPSR1KDM4E | |
| SCHEMBL8942727 | 0.87 | MRGPRX4 (0.47) | MRGPRX4KMT2ANPSR1KDM4EMEN1 | |
| SCHEMBL8439602 | 0.84 | MRGPRX4 (0.45) | MRGPRX4NPSR1KDM4E | |
| SCHEMBL8300515 | 0.83 | GABRA5 (0.34) | MRGPRX4GABRA5KMT2ANPSR1KDM4E | |
| SCHEMBL8304314 | 0.83 | KMT2A (0.48) | KMT2ANPSR1KDM4ELIPEMEN1 | |
| SCHEMBL8303158 | 0.83 | KMT2A (0.48) | KMT2ANPSR1KDM4ELIPEMEN1 | |
| SCHEMBL8942950 | 0.83 | MRGPRX4 (0.48) | MRGPRX4KMT2ANPSR1MEN1ALDH1A1 | |
| SCHEMBL8300716 | 0.82 | KMT2A (0.45) | KMT2ANPSR1KDM4EMEN1POLB | |
| SCHEMBL8304023 | 0.81 | KMT2A (0.44) | KMT2AMEN1POLBMAPT | |
| SCHEMBL8298176 | 0.80 | MRGPRX4 (0.46) | MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482951-A | Triazole derivatives as well as insecticide and acaricide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-01-09 | — | — | US | disclosed |