SCHEMBL8942513

SCHEMBL8942513

Cc1cc([O])c(Oc2ccccc2)c(C)c1Oc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.39
TSHR P16473 2/20 0.39
BRD4 O60885 1/20 0.38
DHODH Q02127 1/20 0.36
KDM4E B2RXH2 2/20 0.36
GLA P06280 2/20 0.36
HPGD P15428 2/20 0.36
ALDH1A1 P00352 1/20 0.36
GAA P10253 1/20 0.36
HSD17B10 Q99714 1/20 0.36
MAPT P10636 2/20 0.36
KMT2A Q03164 2/20 0.36
PGR P06401 1/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TTR P02766 1/20 0.36
GSTP1 P09211 1/20 0.35
POLB P06746 2/20 0.35
MEN1 O00255 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8942434 0.87 LTA4H (0.41) LTA4HTSHRBRD4DHODHKDM4E
SCHEMBL8942482 0.76 LTA4H (0.46) LTA4HTSHRKDM4EGLAHPGD
SCHEMBL8373513 0.74 MAPT (0.42) LTA4HTSHRKDM4EGLAHPGD
SCHEMBL15256759 0.74 TTR (0.50) LTA4HTSHRDHODHKDM4EALDH1A1
SCHEMBL9486844 0.74 LTA4H (0.48) LTA4HTSHRKDM4EGLAHPGD
SCHEMBL9488169 0.74 LTA4H (0.48) LTA4HTSHRKDM4EGLAHPGD
SCHEMBL11583506 0.74 LTA4H (0.48) LTA4HTSHRDHODHKDM4EGLA
SCHEMBL8942231 0.73 LTA4H (0.42) LTA4HTSHRKDM4EGLAHPGD
SCHEMBL11579139 0.73 LTA4H (0.44) LTA4HTSHRBRD4ALDH1A1HTT
SCHEMBL10454874 0.73 KDM4E (0.43) LTA4HTSHRKDM4EGLAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5557003-A SOLVENT EXTRACTION OF ZINC FROM ORE ZENECA LIMITED (GB) 1996-09-17 US disclosed