Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | BAX | Q07812 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13810999 | 0.83 | LTA4H (0.55) | LTA4HTSHRKMT2AMAPTKDM4E | |
| SCHEMBL9486844 | 0.82 | LTA4H (0.48) | LTA4HTSHRKMT2AMAPTKDM4E | |
| SCHEMBL12925863 | 0.79 | LTA4H (0.57) | LTA4HTSHRKMT2AMAOBSMN1; SMN2 | |
| SCHEMBL3331237 | 0.78 | LTA4H (0.44) | LTA4HTSHRKMT2ACYP1A2CYP2C19 | |
| SCHEMBL17628549 | 0.78 | LTA4H (0.44) | LTA4HTSHRKMT2AMAPTKDM4E | |
| SCHEMBL11583506 | 0.77 | LTA4H (0.48) | LTA4HTSHRKMT2AMAPTKDM4E | |
| SCHEMBL9064360 | 0.77 | CYP3A4 (0.32) | TSHRMAPK1 | |
| SCHEMBL2858541 | 0.77 | KDM4E (0.43) | LTA4HTSHRKMT2AMAPTKDM4E | |
| SCHEMBL9487846 | 0.76 | LTA4H (0.52) | LTA4HTSHRKMT2AMAPTKDM4E | |
| SCHEMBL8942482 | 0.76 | LTA4H (0.46) | LTA4HTSHRKMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250657-A | Process for preparing polyarylene thioether | SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) | 1993-10-05 | — | — | US | disclosed |
| EP-0440106-A2 | Process for preparing polyarylene thioethers | SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) | 1991-08-07 | — | — | EP | disclosed |