Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.45 |
| ▸ | NPC1 | O15118 | 8/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.42 |
| ▸ | RELA | Q04206 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945026 | 0.92 | RAB9A (0.44) | RAB9AMAPTL3MBTL1CASP3SENP8 | |
| SCHEMBL9449567 | 0.83 | RAB9A (0.52) | RAB9AMAPTL3MBTL1CASP3SENP8 | |
| SCHEMBL9343407 | 0.83 | RAB9A (0.52) | RAB9AMAPTL3MBTL1CASP3SENP8 | |
| SCHEMBL9345831 | 0.83 | RAB9A (0.52) | RAB9AMAPTL3MBTL1CASP3SENP8 | |
| SCHEMBL9343400 | 0.83 | RAB9A (0.52) | RAB9AMAPTL3MBTL1CASP3SENP8 | |
| SCHEMBL9341801 | 0.83 | RAB9A (0.52) | RAB9AMAPTL3MBTL1CASP3SENP8 | |
| SCHEMBL9346712 | 0.83 | RAB9A (0.52) | RAB9AMAPTL3MBTL1CASP3SENP8 | |
| SCHEMBL10337555 | 0.83 | RAB9A (0.52) | RAB9AMAPTL3MBTL1CASP3SENP8 | |
| SCHEMBL10337414 | 0.83 | RAB9A (0.52) | RAB9AMAPTL3MBTL1CASP3SENP8 | |
| SCHEMBL8942430 | 0.82 | CNR2 (0.39) | RAB9AMAPTL3MBTL1ALDH1A1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |