SCHEMBL8942594

SCHEMBL8942594

CCCCCCCC1CCC(c2ccc(-c3ccc(-c4ccc(OC)c(F)c4F)cc3)c(F)c2F)OC1

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 5/20 0.33
LYPLA1 O75608 1/20 0.31
LYPLA2 O95372 1/20 0.31
ABHD16A O95870 1/20 0.31
SLC6A2 P23975 2/20 0.31
SLC6A4 P31645 2/20 0.31
SLC6A3 Q01959 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPK1 P28482 1/20 0.31
CYP2C19 P33261 1/20 0.31
MGLL Q99685 3/20 0.31
CTDSP1 Q9GZU7 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
PDE4D Q08499 2/20 0.30
PDE4A P27815 1/20 0.30
PDE4B Q07343 1/20 0.30
PDE4C Q08493 1/20 0.30
CNR1 P21554 1/20 0.30
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8942509 0.99 FPR2 (0.33) FPR2LYPLA1LYPLA2ABHD16ASLC6A2
SCHEMBL8942598 0.93 FPR2 (0.32) FPR2
SCHEMBL8942205 0.92 FPR2 (0.32) FPR2
SCHEMBL8942043 0.92 FPR2 (0.35) FPR2SLC6A2SLC6A4SLC6A3
SCHEMBL8941117 0.92 MGLL (0.36) FPR2LYPLA1LYPLA2ABHD16ASLC6A2
SCHEMBL18719108 0.91 MGLL (0.41) FPR2LYPLA1LYPLA2ABHD16ASLC6A2
SCHEMBL18718305 0.91 MGLL (0.37) FPR2LYPLA1LYPLA2ABHD16ASLC6A2
SCHEMBL18719099 0.91 MGLL (0.41) FPR2LYPLA1LYPLA2ABHD16ASLC6A2
SCHEMBL18718313 0.91 MGLL (0.37) FPR2LYPLA1LYPLA2ABHD16ASLC6A2
SCHEMBL8942698 0.91 FPR2 (0.32) FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed