Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | PTPRC | P08575 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31290282 | 1.00 | TSHR (0.57) | TSHRLMNAPTPRCALDH1A1ACHE | |
| SCHEMBL9290836 | 0.89 | ALDH1A1 (0.51) | TSHRLMNAPTPRCALDH1A1ACHE | |
| SCHEMBL9291419 | 0.85 | TP53 (0.55) | TSHRLMNAPTPRCALDH1A1TDP1 | |
| SCHEMBL24710558 | 0.85 | TSHR (0.57) | TSHRLMNAPTPRCALDH1A1ACHE | |
| SCHEMBL11691192 | 0.85 | TSHR (0.57) | TSHRLMNAPTPRCALDH1A1ACHE | |
| SCHEMBL439710 | 0.85 | TSHR (0.61) | TSHRLMNAPTPRCALDH1A1ACHE | |
| SCHEMBL29703748 | 0.85 | TSHR (0.61) | TSHRLMNAPTPRCALDH1A1ACHE | |
| SCHEMBL9291230 | 0.84 | KIF11 (0.45) | TSHRLMNAPTPRCALDH1A1KIF11 | |
| SCHEMBL9778815 | 0.84 | TSHR (0.56) | TSHRLMNAPTPRCALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL155430 | 0.83 | KIF11 (0.59) | TSHRLMNAPTPRCALDH1A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255887-B1 | PROCESS FOR THE PREPARATION OF 2,2-BIS(3-NITROPHENYL)-HEXA-FLUOROPROPANE | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-29 | — | — | EP | claimed |
| US-4774370-A | Process for preparing 2,2-bis-(3-nitrophenyl)-hexafluoropropane, and 2,2-bis-(4-carboxy-3-nitrophenyl)-hexafluoropropane occurring as an intermediate | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-09-27 | — | — | US | claimed |
| EP-0255887-A1 | Process for the preparation of 2,2-bis(3-nitrophenyl)-hexa-fluoropropane | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-02-17 | — | — | EP | claimed |
| JP-8176073-A | — | — | None | — | — | JP | disclosed |
| JP-H08176073-A | 2,2-BIS-(4-CARBOXY-3-NITROPHENYL)-HEXAFLUOROPROPANE | HOECHST AG | 1996-07-09 | — | — | JP | disclosed |
| US-5283285-A | Comprising an amine functionalized elastomer, a graft coupling agent; molding materials for sport, technical, household equipement; heat and chemical resistance | ALLIEDSIGNAL INC. (US) | 1994-02-01 | — | — | US | disclosed |
| EP-0297570-B1 | 2,2-BIS-(3-AMINOPHENYL)-HEXAFLUOROPROPANE DERIVATIVES AND PROCESS FOR THE PREPARATION OF 2,2-BIS-(3,4-DIAMINOPHENYL)-HEXAFLUOROPROPANE | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-06-05 | — | — | EP | disclosed |
| EP-0255887-B1 | PROCESS FOR THE PREPARATION OF 2,2-BIS(3-NITROPHENYL)-HEXA-FLUOROPROPANE | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-29 | — | — | EP | disclosed |
| EP-0255887-B1 | PROCESS FOR THE PREPARATION OF 2,2-BIS(3-NITROPHENYL)-HEXA-FLUOROPROPANE | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-29 | — | — | EP | disclosed |
| US-4922019-A | Derivatives of 2,2-bis-(3-aminophenyl)hexafluoropropane and process for the preparation of 2,2-bis-(3,4-diaminophenyl)hexafluoropropane | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-05-01 | — | — | US | disclosed |
| EP-0297570-A2 | 2,2-Bis-(3-aminophenyl)-hexafluoropropane derivatives and process for the preparation of 2,2-bis-(3,4-diaminophenyl)-hexafluoropropane | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-01-04 | — | — | EP | disclosed |
| US-4774370-A | Process for preparing 2,2-bis-(3-nitrophenyl)-hexafluoropropane, and 2,2-bis-(4-carboxy-3-nitrophenyl)-hexafluoropropane occurring as an intermediate | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-09-27 | — | — | US | disclosed |
| US-4774370-A | Process for preparing 2,2-bis-(3-nitrophenyl)-hexafluoropropane, and 2,2-bis-(4-carboxy-3-nitrophenyl)-hexafluoropropane occurring as an intermediate | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-09-27 | — | — | US | disclosed |
| EP-0255887-A1 | Process for the preparation of 2,2-bis(3-nitrophenyl)-hexa-fluoropropane | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-02-17 | — | — | EP | disclosed |
| EP-0255887-A1 | Process for the preparation of 2,2-bis(3-nitrophenyl)-hexa-fluoropropane | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-02-17 | — | — | EP | disclosed |
| EP-0255887-A1 | Process for the preparation of 2,2-bis(3-nitrophenyl)-hexa-fluoropropane | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-02-17 | — | — | EP | disclosed |
| US-4720590-A | [2,2,2-trihalo-1-(trihalomethyl)]ethylidene-bisbenzenethiols | HUGHES AIRCRAFT COMPANY (US) | 1988-01-19 | — | — | US | disclosed |
| EP-0129561-B1 | 2,2,2-TRIHALO-1-(TRIHALOMETHYL)ETHYLIDENE-BISBENZENETHIOLS | Hughes Aircraft Company (US) | 1986-02-12 | — | — | EP | disclosed |
| EP-0129561-A1 | 2,2,2-TRIHALO-1-(TRIHALOMETHYL)ETHYLIDENE-BISBENZENETHIOLS. | HUGHES AIRCRAFT CO (US) | 1985-01-02 | — | — | EP | disclosed |
| WO-1984002524-A1 | 2,2,2-TRIHALO-1-(TRIHALOMETHYL)ETHYLIDENE-BISBENZENETHIOLS | HUGHES AIRCRAFT CO (US) | 1984-07-05 | — | — | WO | disclosed |