Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | TEK | Q02763 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942725 | 0.87 | NR1H2 (0.49) | NR1H2NR1H3KMT2AMEN1NPC1 | |
| SCHEMBL8942970 | 0.85 | HSD17B2 (0.50) | NR1H2NR1H3KMT2ANPC1RAB9A | |
| SCHEMBL8304172 | 0.85 | PSEN1 (0.42) | NR1H2NR1H3KMT2AMEN1HSD17B2 | |
| SCHEMBL5727077 | 0.84 | KMT2A (0.37) | KMT2AMEN1NPC1RAB9AKDM4C | |
| SCHEMBL9049556 | 0.84 | MAPT (0.43) | NR1H2NR1H3KMT2AMEN1NPC1 | |
| SCHEMBL8942539 | 0.82 | NR1H2 (0.44) | NR1H2NR1H3KMT2AMEN1NPC1 | |
| SCHEMBL8942480 | 0.82 | NR1H2 (0.44) | NR1H2NR1H3KMT2AMEN1NPC1 | |
| SCHEMBL8304815 | 0.81 | NR1H2 (0.43) | NR1H2NR1H3KMT2ANPC1RAB9A | |
| SCHEMBL6951559 | 0.81 | MEN1 (0.45) | NR1H2NR1H3KMT2AMEN1NPC1 | |
| SCHEMBL8942557 | 0.80 | KMT2A (0.48) | KMT2AMEN1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482951-A | Triazole derivatives as well as insecticide and acaricide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-01-09 | — | — | US | disclosed |