Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MDM4 | O15151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | YES1 | P07947 | 2/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942725 | 0.90 | NR1H2 (0.49) | HSD17B2NR1H2NR1H3NPC1RAB9A | |
| SCHEMBL8942539 | 0.86 | NR1H2 (0.44) | HSD17B2NR1H2NR1H3NPC1RAB9A | |
| SCHEMBL8303453 | 0.86 | HSD17B2 (0.44) | HSD17B2NR1H2NR1H3NPC1RAB9A | |
| SCHEMBL5726494 | 0.85 | HSD17B2 (0.40) | HSD17B2NR1H2NR1H3NPC1RAB9A | |
| SCHEMBL8942833 | 0.85 | NR1H2 (0.45) | HSD17B2NR1H2NR1H3NPC1RAB9A | |
| SCHEMBL8942480 | 0.84 | NR1H2 (0.44) | HSD17B2NR1H2NR1H3NPC1RAB9A | |
| SCHEMBL5727617 | 0.84 | HSD17B2 (0.36) | HSD17B2NR1H2NR1H3KDM4CKMT2A | |
| SCHEMBL6074574 | 0.84 | HSD17B2 (0.36) | HSD17B2NR1H2NR1H3KDM4CKMT2A | |
| SCHEMBL5726399 | 0.84 | HSD17B2 (0.36) | HSD17B2NR1H2NR1H3KDM4CPDE2A | |
| SCHEMBL8304815 | 0.84 | NR1H2 (0.43) | HSD17B2NR1H2NR1H3NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482951-A | Triazole derivatives as well as insecticide and acaricide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-01-09 | — | — | US | disclosed |