Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.55 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 3/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28578725 | 0.81 | HDAC1 (0.60) | HDAC1HDAC2KCNA3PPARAHDAC3 | |
| SCHEMBL11617521 | 0.81 | HDAC1 (0.65) | HDAC1HDAC2KCNA3PPARAHDAC3 | |
| SCHEMBL11577655 | 0.81 | HDAC1 (0.65) | HDAC1HDAC2KCNA3PPARAHDAC3 | |
| SCHEMBL5133484 | 0.81 | HDAC1 (0.60) | HDAC1HDAC2KCNA3PPARAHDAC3 | |
| SCHEMBL6335494 | 0.79 | HDAC1 (0.63) | HDAC1HDAC2KCNA3PPARAHDAC3 | |
| SCHEMBL23082440 | 0.79 | HDAC1 (0.63) | HDAC1HDAC2PPARAHDAC3HDAC4 | |
| SCHEMBL80061 | 0.79 | ALOX15 (0.59) | THRBMEN1ALPLALPIALPG | |
| SCHEMBL10336969 | 0.79 | THRB (0.59) | HDAC1HDAC2KCNA3PPARATDP1 | |
| SCHEMBL7773717 | 0.79 | HDAC1 (0.62) | HDAC1HDAC2KCNA3PPARAHDAC3 | |
| SCHEMBL1162023 | 0.78 | PPARA (0.74) | HDAC1HDAC2KCNA3PPARAHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160317201-A1 | BONE STABILIZATION DEVICE AND METHOD | FLEXFIX, LLC (US) | 2016-11-03 | — | — | US | disclosed |
| US-9421045-B2 | Bone stabilization device and method | FLEXFIX, LLC (US) | 2016-08-23 | — | — | US | disclosed |
| US-20160128742-A9 | BONE STABILIZATION DEVICE AND METHOD | OSTEOLIGN, INC. | 2016-05-12 | — | — | US | disclosed |
| US-8834468-B2 | Bone stabilization device and method | FLEXFIX, LLC (US) | 2014-09-16 | — | — | US | disclosed |
| US-20140207138-A1 | BONE STABILIZATION DEVICE AND METHOD | FLEXFIX LLC (US) | 2014-07-24 | — | — | US | disclosed |
| US-20120239037-A1 | BONE STABILIZATION DEVICE AND METHOD | FLEXFIX LLC (US) | 2012-09-20 | — | — | US | disclosed |
| US-8167881-B2 | Implantable composite apparatus and method | FLEXFIX, LLC (US) | 2012-05-01 | — | — | US | disclosed |
| US-8162943-B2 | Deformable implant systems and methods | FLEXFIX, LLC (US) | 2012-04-24 | — | — | US | disclosed |
| US-8147492-B2 | System and method for guidance and implantation of implantable devices | FLEXFIX, LLC (US) | 2012-04-03 | — | — | US | disclosed |
| US-8128626-B2 | System and method for delivery conformation and removal of intramedullary bone fixation devices | FLEXFIX, LLC (US) | 2012-03-06 | — | — | US | disclosed |
| WO-2010091242-A1 | PROXIMAL FEMUR FIXATION APPARATUS, SYSTEMS AND METHODS WITH ANGLED ELONGATE ELEMENTS | NOVALIGN ORTHOPAEDICS, INC. (US) | 2010-08-12 | — | — | WO | disclosed |
| EP-2139432-A2 | DEFORMABLE IMPLANT SYSTEMS AND METHODS | Novalign Orthopaedics, Inc. (US) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008134287-A2 | DEFORMABLE IMPLANT SYSTEMS AND METHODS | NOVALIGN ORTHOPAEDICS, INC. (US) | 2008-11-06 | — | — | WO | disclosed |
| US-20080269747-A1 | SYSTEM AND METHOD FOR DELIVERY, CONFORMATION AND REMOVAL OF INTRAMEDULLARY BONE FIXATION DEVICES | OSTEOLIGN, INC. (US) | 2008-10-30 | — | — | US | disclosed |
| US-20080269746-A1 | CONFORMABLE INTRAMEDULLARY IMPLANT WITH NESTABLE COMPONENTS | OSTEOLIGN, INC. (US) | 2008-10-30 | — | — | US | disclosed |
| US-20080269776-A1 | System and Method for Guidance and Implantation of Implantable Devices | OSTEOLIGN (US) | 2008-10-30 | — | — | US | disclosed |
| US-20080269745-A1 | THERMO-CHEMICALLY ACTIVATED INTRAMEDULLARY BONE STENT | OSTEOLIGN, INC. (US) | 2008-10-30 | — | — | US | disclosed |
| US-20080269748-A1 | Deformable Implant Systems and Methods | OSTEOLIGN (US) | 2008-10-30 | — | — | US | disclosed |
| US-20080269749-A1 | Thermo-Chemically Activated Implantable Apparatus and Method | OSTEOLIGN (US) | 2008-10-30 | — | — | US | disclosed |
| US-20080269750-A1 | Implantable Composite Apparatus and Method | OSTEOLIGN (US) | 2008-10-30 | — | — | US | disclosed |