SCHEMBL8942919

SCHEMBL8942919

O=[N+]([O-])c1ccc2[nH]c(-c3cc4cc5ccccc5cc4cc3O)nc2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPBWR1 P48145 8/20 0.53
F2 P00734 1/20 0.52
F10 P00742 1/20 0.52
PLG P00747 1/20 0.52
PLAU P00749 1/20 0.52
PLAT P00750 1/20 0.52
PRSS1 P07477 1/20 0.52
MAPT P10636 6/20 0.51
RAB9A P51151 4/20 0.51
NPC1 O15118 3/20 0.51
SMN1; SMN2 Q16637 3/20 0.51
MMP2 P08253 2/20 0.50
MMP9 P14780 2/20 0.50
MMP8 P22894 2/20 0.50
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
AMY1A P0DUB6 2/20 0.47
CHEK2 O96017 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
NPSR1 Q6W5P4 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10579818 0.97 NPBWR1 (0.55) NPBWR1F2F10PLGPLAU
SCHEMBL2250346 0.86 NPBWR1 (0.60) NPBWR1F2F10PLGPLAU
SCHEMBL4497810 0.85 NPBWR1 (0.65) NPBWR1MAPTRAB9ANPC1SMN1; SMN2
SCHEMBL4487881 0.82 MMP2 (0.66) NPBWR1MAPTRAB9ANPC1SMN1; SMN2
SCHEMBL4497816 0.81 NPBWR1 (0.74) NPBWR1MAPTRAB9ANPC1SMN1; SMN2
SCHEMBL7394835 0.80 NPBWR1 (0.61) NPBWR1F2F10PLGPLAU
SCHEMBL19064513 0.80 F2 (0.57) NPBWR1F2F10PLGPLAU
SCHEMBL8942820 0.80 KDR (0.61) MAPTRAB9ANPC1SMN1; SMN2MEN1
SCHEMBL3337243 0.80 NPBWR1 (0.81) NPBWR1MAPTRAB9ANPC1SMN1; SMN2
SCHEMBL3202735 0.80 NPBWR1 (0.81) NPBWR1MAPTRAB9ANPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5501927-A DISAZO OR TRISAZO DYES FUJI XEROX CO., LTD. (JP) 1996-03-26 US disclosed