Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 15/20 | 0.57 |
| ▸ | AGTR2 | P50052 | 9/20 | 0.57 |
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942670 | 0.93 | AGTR1 (0.67) | AGTR1AGTR2PPARG | |
| SCHEMBL9410759 | 0.86 | AGTR1 (0.50) | AGTR1AGTR2 | |
| SCHEMBL8942772 | 0.84 | PPARG (0.62) | AGTR1AGTR2PPARG | |
| SCHEMBL4884818 | 0.84 | AGTR1 (0.60) | AGTR1AGTR2PPARG | |
| SCHEMBL8872802 | 0.83 | AGTR1 (0.64) | AGTR1AGTR2 | |
| SCHEMBL3642104 | 0.83 | PPARG (0.76) | AGTR1AGTR2PPARG | |
| SCHEMBL12606480 | 0.81 | AGTR1 (0.73) | AGTR1AGTR2 | |
| SCHEMBL8847682 | 0.81 | AGTR1 (0.66) | AGTR1AGTR2 | |
| SCHEMBL14855532 | 0.81 | AGTR1 (0.65) | AGTR1AGTR2PPARG | |
| SCHEMBL4553370 | 0.81 | AGTR1 (0.65) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521177-A | ANGIOTENSIN ANTAGONIST FOR CARDIOVASCULAR DISORDERS SUCH AS ISCHEMIA OR CENTRAL NERVOUS SYSTEM DISORDERS SUCH AS COGNITIVE FUNCTIONS, DEPRESSION, ALZHEIMER'S DISEASE OR PARKINSON'S SYNDROME | DR. KARL THOMAE GMBH (DE) | 1996-05-28 | — | — | US | disclosed |