Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19201526 | 1.00 | TDP1 (0.48) | TDP1PABPC1APOBEC3AAPOBEC3GCA1 | |
| SCHEMBL6562442 | 1.00 | TDP1 (0.48) | TDP1PABPC1APOBEC3AAPOBEC3GCA1 | |
| SCHEMBL2128168 | 1.00 | TDP1 (0.48) | TDP1PABPC1APOBEC3AAPOBEC3GCA1 | |
| SCHEMBL6564377 | 1.00 | TDP1 (0.48) | TDP1PABPC1APOBEC3AAPOBEC3GCA1 | |
| SCHEMBL129425 | 0.96 | TDP1 (0.50) | TDP1PABPC1APOBEC3AAPOBEC3GCA1 | |
| SCHEMBL44781 | 0.96 | TDP1 (0.50) | TDP1PABPC1APOBEC3AAPOBEC3GCA1 | |
| SCHEMBL130804 | 0.96 | TDP1 (0.50) | TDP1PABPC1APOBEC3AAPOBEC3GCA1 | |
| SCHEMBL33424 | 0.96 | TDP1 (0.50) | TDP1PABPC1APOBEC3AAPOBEC3GCA1 | |
| SCHEMBL12816270 | 0.96 | TDP1 (0.50) | TDP1PABPC1APOBEC3AAPOBEC3GCA1 | |
| SCHEMBL130805 | 0.96 | TDP1 (0.50) | TDP1PABPC1APOBEC3AAPOBEC3GCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0614457-B1 | LEUKOTRIENE-B 4? DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS | SCHERING AG (DE) | 1996-08-21 | — | — | EP | disclosed |
| US-5502075-A | Leukotriene-B4 derivatives, process for their production and their use as pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-03-26 | — | — | US | disclosed |