SCHEMBL130805

SCHEMBL130805

OC[C@@H]1CCCC[C@H]1CO

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.50
PABPC1 P11940 1/20 0.44
APOBEC3A P31941 1/20 0.44
APOBEC3G Q9HC16 1/20 0.44
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA4 P22748 1/20 0.38
GBA1 P04062 6/20 0.37
TSHR P16473 1/20 0.35
SI P14410 1/20 0.32
PYGL P06737 1/20 0.32
GBA2 Q9HCG7 1/20 0.32
GAA P10253 1/20 0.32
GLB1 P16278 1/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33424 1.00 TDP1 (0.50) TDP1PABPC1APOBEC3AAPOBEC3GCA1
SCHEMBL12816270 1.00 TDP1 (0.50) TDP1PABPC1APOBEC3AAPOBEC3GCA1
SCHEMBL129425 1.00 TDP1 (0.50) TDP1PABPC1APOBEC3AAPOBEC3GCA1
SCHEMBL130804 1.00 TDP1 (0.50) TDP1PABPC1APOBEC3AAPOBEC3GCA1
SCHEMBL44781 1.00 TDP1 (0.50) TDP1PABPC1APOBEC3AAPOBEC3GCA1
SCHEMBL8943002 0.96 TDP1 (0.48) TDP1PABPC1APOBEC3AAPOBEC3GCA1
SCHEMBL19201526 0.96 TDP1 (0.48) TDP1PABPC1APOBEC3AAPOBEC3GCA1
SCHEMBL6564377 0.96 TDP1 (0.48) TDP1PABPC1APOBEC3AAPOBEC3GCA1
SCHEMBL2128168 0.96 TDP1 (0.48) TDP1PABPC1APOBEC3AAPOBEC3GCA1
SCHEMBL6562442 0.96 TDP1 (0.48) TDP1PABPC1APOBEC3AAPOBEC3GCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 277 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116478382-A Aromatic heat-resistant toughened polyester and preparation method thereof 复旦大学 2023-07-25 CN claimed
CN-116135866-A Bridged carboxylic acid-containing difunctional phosphine ligand, preparation method and application thereof 中山大学 2023-05-19 CN claimed
CN-109336887-B Benzimidazole chiral heterocyclic compound and preparation method and application thereof 中山大学 2021-12-17 CN claimed
CN-212845213-U Detection apparatus for (1R,2R) -1, 2-cyclohexanedimethanol isomer 石家庄四药有限公司 2021-03-30 CN claimed
CN-106831862-B Chiral bridged axial chiral monophosphine ligand and preparation method thereof 中山大学 2021-01-15 CN claimed
CN-112083104-A Method and device for detecting isomer of (1R,2R) -1, 2-cyclohexanedimethanol 石家庄四药有限公司 2020-12-15 CN claimed
CN-107688069-B Method for detecting (1R,2R) -cyclohexane-1, 2-dimethanol 顾世海 2020-11-03 CN claimed
US-10426770-B2 Process for the preparation of Lurasidone hydrochloride Jubilant Generics Limited (IN) 2019-10-01 US claimed
CN-104610363-B Phosphorous amide ligand and its preparation method and application 中山大学 2018-04-10 CN claimed
US-20170246165-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF LURASIDONE HYDROCHLORIDE Jubilant Generics Limited (IN) 2017-08-31 US claimed
US-20130237642-A1 THERMOSETTABLE COMPOSITIONS AND THERMOSETS THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2013-09-12 US claimed
WO-2013121440-A1 PROCESS FOR PREPARING BENZISOTHIAZOL-3-YL-PEPERAZIN-L-YL-METHYL-CYCLO HEXYL-METHANISOINDOL-1,3-DIONE AND ITS INTERMEDIATES CADILA HEALTHCARE LIMITED (IN) 2013-08-22 WO claimed
EP-2621994-A1 EPOXY RESIN COMPOSITIONS Dow Global Technologies LLC (US) 2013-08-07 EP claimed
EP-2621991-A1 PROCESS FOR PREPARING EPOXY RESINS Dow Global Technologies LLC (US) 2013-08-07 EP claimed
EP-2621990-A2 THERMOSETTABLE COMPOSITIONS AND THERMOSETS THEREFROM Dow Global Technologies LLC (US) 2013-08-07 EP claimed
US-20130178601-A1 PROCESS FOR PREPARING EPOXY RESINS DOW GLOBAL TECHNOLOGIES LLC (US) 2013-07-11 US claimed
WO-2012131606-A1 PROCESS FOR THE PREPARATION OF AN ANTIPSYCHOTIC AGENT RANBAXY LABORATORIES LIMITED (IN) 2012-10-04 WO claimed
WO-2012047420-A2 THERMOSETTABLE COMPOSITIONS AND THERMOSETS THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2012-04-12 WO claimed
WO-2012044442-A1 PROCESS FOR PREPARING EPOXY RESINS DOW GLOBAL TECHNOLOGIES LLC (US) 2012-04-05 WO claimed
WO-2012044443-A1 EPOXY RESIN COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2012-04-05 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170246165-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF LURASIDONE HYDROCHLORIDE FFAR3, FAR1, PRLHR TDP1 4632/4885PABPC1 4716/4885APOBEC3A 4361/4885
US-10426770-B2 Process for the preparation of Lurasidone hydrochloride FFAR3, REN, LSS TDP1 4699/4885PABPC1 4747/4885APOBEC3A 4456/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.