Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 6/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | PYGL | P06737 | 1/20 | 0.32 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GLB1 | P16278 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33424 | 1.00 | TDP1 (0.50) | TDP1PABPC1APOBEC3AAPOBEC3GCA1 | |
| SCHEMBL12816270 | 1.00 | TDP1 (0.50) | TDP1PABPC1APOBEC3AAPOBEC3GCA1 | |
| SCHEMBL130804 | 1.00 | TDP1 (0.50) | TDP1PABPC1APOBEC3AAPOBEC3GCA1 | |
| SCHEMBL44781 | 1.00 | TDP1 (0.50) | TDP1PABPC1APOBEC3AAPOBEC3GCA1 | |
| SCHEMBL130805 | 1.00 | TDP1 (0.50) | TDP1PABPC1APOBEC3AAPOBEC3GCA1 | |
| SCHEMBL8943002 | 0.96 | TDP1 (0.48) | TDP1PABPC1APOBEC3AAPOBEC3GCA1 | |
| SCHEMBL19201526 | 0.96 | TDP1 (0.48) | TDP1PABPC1APOBEC3AAPOBEC3GCA1 | |
| SCHEMBL6564377 | 0.96 | TDP1 (0.48) | TDP1PABPC1APOBEC3AAPOBEC3GCA1 | |
| SCHEMBL2128168 | 0.96 | TDP1 (0.48) | TDP1PABPC1APOBEC3AAPOBEC3GCA1 | |
| SCHEMBL6562442 | 0.96 | TDP1 (0.48) | TDP1PABPC1APOBEC3AAPOBEC3GCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 423 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116478382-A | Aromatic heat-resistant toughened polyester and preparation method thereof | 复旦大学 | 2023-07-25 | — | — | CN | claimed |
| CN-114316197-B | Thermoplastic polyurethane adhesive with low polarity and high heat resistance and application thereof | 万华化学集团股份有限公司 | 2023-07-14 | — | — | CN | claimed |
| CN-116135866-A | Bridged carboxylic acid-containing difunctional phosphine ligand, preparation method and application thereof | 中山大学 | 2023-05-19 | — | — | CN | claimed |
| CN-115785880-A | Polyurethane adhesive and preparation method and application thereof | 万华化学集团股份有限公司 | 2023-03-14 | — | — | CN | claimed |
| CN-114316197-A | Low-polarity high-heat-resistance thermoplastic polyurethane adhesive and application thereof | 万华化学集团股份有限公司 | 2022-04-12 | — | — | CN | claimed |
| CN-109336887-B | Benzimidazole chiral heterocyclic compound and preparation method and application thereof | 中山大学 | 2021-12-17 | — | — | CN | claimed |
| CN-106831862-B | Chiral bridged axial chiral monophosphine ligand and preparation method thereof | 中山大学 | 2021-01-15 | — | — | CN | claimed |
| CN-109336887-A | A kind of benzimidazole and chiral heterocycle class compound and its preparation method and application | 中山大学 | 2019-02-15 | — | — | CN | claimed |
| CN-104610363-B | Phosphorous amide ligand and its preparation method and application | 中山大学 | 2018-04-10 | — | — | CN | claimed |
| CN-106831862-A | Axial chirality monophosphorus ligand of one class chirality bridging and preparation method thereof | 中山大学 | 2017-06-13 | — | — | CN | claimed |
| CN-102532196-B | Phosphine ligands and enantiomorph or raceme and preparation method thereof | SUN YAT-SEN UNIVERSITY (CN) | 2015-09-02 | — | — | CN | claimed |
| CN-104610363-A | Phosphoramidite ligand as well as preparation method and application thereof | UNIV SUN YAT SEN | 2015-05-13 | — | — | CN | claimed |
| US-8318834-B2 | Epoxy resin reactive diluent compositions | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-11-27 | — | — | US | claimed |
| US-20110046266-A1 | EPOXY RESIN REACTIVE DILUENT COMPOSITIONS | BLUE CUBE IP LLC | 2011-02-24 | — | — | US | claimed |
| EP-2283093-A1 | EPOXY RESIN REACTIVE DILUENT COMPOSITIONS | Dow Global Technologies Inc. (US) | 2011-02-16 | — | — | EP | claimed |
| WO-2009142900-A1 | EPOXY RESIN REACTIVE DILUENT COMPOSITIONS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2009-11-26 | — | — | WO | claimed |
| US-20020141952-A1 | Regulating the melanin content of mammalian melanocytes by administering alcohols, diols, triols and their analogues | APPLIED GENETICS INCORPORATED DERMATICS | 2002-10-03 | — | — | US | claimed |
| WO-2002051395-A1 | TREATMENT OF NEURODEGENERATIVE DISEASES | CODON PHARMACEUTICALS, INC. (US) | 2002-07-04 | — | — | WO | claimed |
| WO-1998055085-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS | CODON PHARMACEUTICALS, INC. (US) | 1998-12-10 | — | — | WO | claimed |
| US-5169438-A | Storage stability, quick-drying | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-12-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020141952-A1 | Regulating the melanin content of mammalian melanocytes by administering alcohols, diols, triols and their analogues | TYR, MITF, MC1R | TDP1 1802/4885PABPC1 4496/4885APOBEC3A 3853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.