Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622203 | 0.79 | SLC6A4 (0.33) | CYP2C19SLC6A4SMN1; SMN2 | |
| SCHEMBL1838203 | 0.78 | TSHR (0.53) | TSHRGABRA1GABRB2SLC6A4POLB | |
| SCHEMBL27816063 | 0.78 | SLC6A4 (0.50) | TSHRCYP2C19SLC6A4SMN1; SMN2KDM4E | |
| SCHEMBL11499036 | 0.77 | TSHR (0.45) | TSHRCYP2C19GABRA1GABRB2POLB | |
| SCHEMBL1838475 | 0.75 | TSHR (0.46) | TSHRGABRA1GABRB2SLC6A4POLB | |
| SCHEMBL8591085 | 0.75 | ALDH1A1 (0.32) | SLC6A4HPGDSMN1; SMN2 | |
| SCHEMBL6535412 | 0.74 | SLC6A4 (0.37) | TSHRGABRA1GABRB2SLC6A4POLB | |
| SCHEMBL1835460 | 0.73 | TSHR (0.43) | TSHRGABRA1GABRB2SLC6A4POLB | |
| SCHEMBL8593657 | 0.73 | CYP2C19 (0.32) | CYP2C19MEN1KMT2A | |
| SCHEMBL8593655 | 0.73 | CYP2C19 (0.32) | CYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0467721-B1 | Optically active compound having a delta- valerolactone ring and liquid crystal composition containing same | MITSUBISHI RAYON CO (JP) | 1996-03-27 | — | — | EP | disclosed |
| US-5480580-A | COMPOUNDS FOR VISUAL AIDS WITH GOOD STABILITY | MITSUBISHI RAYON COMPANY LTD. (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0467721-A1 | Optically active compound having a delta- valerolactone ring and liquid crystal composition containing same | MITSUBISHI RAYON CO., LTD (JP) | 1992-01-22 | — | — | EP | disclosed |