Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8591085 | 0.82 | ALDH1A1 (0.32) | SLC6A4SMN1; SMN2 | |
| SCHEMBL8943022 | 0.79 | TSHR (0.37) | SLC6A4CYP2C19SMN1; SMN2 | |
| SCHEMBL27816063 | 0.76 | SLC6A4 (0.50) | SLC6A4CYP2C19SMN1; SMN2 | |
| SCHEMBL27722724 | 0.71 | CYP2C19 (0.37) | SLC6A4CYP2C19PPARGPPARASMN1; SMN2 | |
| SCHEMBL8089903 | 0.71 | CYP2C19 (0.39) | SLC6A4CYP2C19PPARGPPARASMN1; SMN2 | |
| SCHEMBL1778182 | 0.70 | CYP2C19 (0.41) | SLC6A4CYP2C19SMN1; SMN2ATML3MBTL1 | |
| SCHEMBL18228722 | 0.70 | SLC6A4 (0.56) | SLC6A4PPARGPPARAATML3MBTL1 | |
| SCHEMBL8593657 | 0.69 | CYP2C19 (0.32) | CYP2C19 | |
| SCHEMBL8593655 | 0.69 | CYP2C19 (0.32) | CYP2C19 | |
| SCHEMBL4711438 | 0.69 | CYP2C19 (0.40) | SLC6A4CYP2C19PPARGPPARASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658541-B1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5510506-A | Process for producing carboxylic acid derivatives | SHIONOGI & CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0658541-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |