Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5092329 | 0.84 | CYP1A2 (0.48) | CYP1A2ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL1720666 | 0.82 | CYP1A2 (0.52) | CYP1A2ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL7013448 | 0.82 | ALDH1A1 (0.50) | CYP1A2ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL8686002 | 0.81 | CYP1A2 (0.50) | CYP1A2ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL5025130 | 0.79 | CYP1A2 (0.44) | CYP1A2ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL1808983 | 0.78 | CYP1A2 (0.43) | CYP1A2ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL8687010 | 0.77 | KDM4E (0.49) | CYP1A2ALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL8687107 | 0.75 | TSHR (0.45) | CYP1A2ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL8943071 | 0.74 | KDM4E (0.41) | CYP1A2ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL23610342 | 0.74 | HTT (0.64) | ALDH1A1KDM4ESMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5529977-A | A 3-ALKOXYBUTYRYLIMIDAZOLE COMPOUND | UBE INDUSTRIES, LTD. (JP) | 1996-06-25 | — | — | US | disclosed |
| US-5387575-A | Pyrimidine derivatives, process for preparing the same and herbicide using the same | UBE INDUSTRIES, LTD. (JP) | 1995-02-07 | — | — | US | disclosed |
| EP-0517215-A1 | Pyrimidine or triazine derivative, process for preparing the same and herbicide using the same | UBE INDUSTRIES, LTD. (JP) | 1992-12-09 | — | — | EP | disclosed |