Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CTSA | P10619 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9461180 | 0.89 | ALDH1A1 (0.44) | ALDH1A1KDM4ECYP1A2LMNATDP1 | |
| SCHEMBL5092329 | 0.86 | CYP1A2 (0.48) | ALDH1A1KDM4ECYP1A2LMNATDP1 | |
| SCHEMBL1720666 | 0.84 | CYP1A2 (0.52) | ALDH1A1KDM4ECYP1A2LMNATDP1 | |
| SCHEMBL8943069 | 0.82 | CYP1A2 (0.46) | ALDH1A1KDM4ECYP1A2LMNATDP1 | |
| SCHEMBL8686002 | 0.82 | CYP1A2 (0.50) | ALDH1A1KDM4ECYP1A2LMNATDP1 | |
| SCHEMBL3444212 | 0.82 | PTGS1 (0.53) | ALDH1A1KDM4ECYP1A2LMNATDP1 | |
| SCHEMBL1921603 | 0.81 | THRB (0.45) | ALDH1A1CYP1A2SMN1; SMN2GLAMAPT | |
| SCHEMBL5717600 | 0.81 | KDM4E (0.47) | ALDH1A1KDM4ECYP1A2LMNATDP1 | |
| SCHEMBL5025130 | 0.81 | CYP1A2 (0.44) | ALDH1A1KDM4ECYP1A2LMNATDP1 | |
| SCHEMBL8943071 | 0.80 | KDM4E (0.41) | ALDH1A1KDM4ECYP1A2LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353640-B2 | Heterocyclic N-acylsulphonamides, process for their preparation, agents containing them and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE GMBH (DE) | 2003-10-15 | — | — | EP | disclosed |
| EP-0353640-B1 | Heterocyclic N-acylsulphonamides, process for their preparation, agents containing them and their use as herbicides and plant growth regulators | HOECHST SCHERING AGREVO GMBH (DE) | 1995-04-12 | — | — | EP | disclosed |
| US-5317005-A | Pyrimidinyl and triazinyl herbicides | SCHERING AGROCHEMICALS LIMITED (GB) | 1994-05-31 | — | — | US | disclosed |
| EP-0539427-A1 | PYRIMIDINYL AND TRIAZINYL HERBICIDES | AgrEvo UK Limited (GB) | 1993-05-05 | — | — | EP | disclosed |
| US-5186736-A | Pre- and postemergence | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-02-16 | — | — | US | disclosed |
| WO-1992001677-A1 | PYRIMIDINYL AND TRIAZINYL HERBICIDES | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-02-06 | — | — | WO | disclosed |
| US-5053072-A | HETEROCYCLIC N-ACYLSULFONAMIDES, AND THEIR USE AS HERBICIDES OR GROWTH REGULATORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-01 | — | — | US | disclosed |
| EP-0353640-A2 | Heterocyclic N-acylsulphonamides, process for their preparation, agents containing them and their use as herbicides and plant growth regulators | Hoechst Schering AgrEvo GmbH (DE) | 1990-02-07 | — | — | EP | disclosed |