SCHEMBL8943124

SCHEMBL8943124

Cc1cc(F)ccc1N.Cc1ccc(F)cc1N

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 6/20 0.48
ALDH1A1 P00352 5/20 0.48
TDP1 Q9NUW8 5/20 0.48
TSHR P16473 3/20 0.48
CASP1 P29466 1/20 0.48
CYP1A1 P04798 1/20 0.46
MEN1 O00255 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
KMT2A Q03164 1/20 0.43
S100B P04271 1/20 0.42
MAPK1 P28482 1/20 0.42
MAPT P10636 1/20 0.41
KEAP1 Q14145 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
SKP2 Q13309 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29502013 0.91
SCHEMBL29722285 0.91
SCHEMBL102467 0.91
SCHEMBL291685 0.91
Ammonia Solution, Strong SCHEMBL28156672 0.89 CYP3A4 (0.54) CYP3A4ALDH1A1TDP1TSHRCYP1A1
Hydrochloric Acid SCHEMBL11831950 0.89 CYP3A4 (0.54) CYP3A4ALDH1A1TDP1TSHRCYP1A1
Nitrogen SCHEMBL28363310 0.86 CYP3A4 (0.52) CYP3A4ALDH1A1TDP1TSHRCYP1A1
Formic Acid SCHEMBL27819476 0.79 KEAP1 (0.46) CYP3A4ALDH1A1TDP1TSHRMEN1
Formic Acid Methyl Ester SCHEMBL23716948 0.76 ALDH1A1 (0.42) CYP3A4ALDH1A1TDP1TSHRCASP1
Formic Acid Methyl Ester SCHEMBL28237553 0.76 ALDH1A1 (0.42) CYP3A4ALDH1A1TDP1TSHRCYP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0710257-A1 IMIDO TRANSITION METAL COMPLEX METATHESIS CATALYSTS SHELL OIL CO (US) 1996-05-08 EP disclosed
WO-1995003346-A1 IMIDO TRANSITION METAL COMPLEX METATHESIS CATALYSTS SHELL OIL COMPANY (US) 1995-02-02 WO disclosed