SCHEMBL8943182

SCHEMBL8943182

CCC(=Cc1sc2ccc(Cl)cc2[n+]1CCCS(=O)(=O)O)C=C1Sc2ccc(Cl)cc2N1CCCS(=O)(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.56
▸ MEN1 O00255 5/20 0.56
▸ KMT2A Q03164 5/20 0.56
▸ THRB P10828 4/20 0.56
▸ RECQL P46063 4/20 0.56
▸ BLM P54132 3/20 0.56
▸ MAPK1 P28482 3/20 0.56
▸ TDP1 Q9NUW8 3/20 0.56
▸ L3MBTL1 Q9Y468 3/20 0.56
▸ RAD52 P43351 3/20 0.56
▸ ALDH1A1 P00352 2/20 0.56
▸ POLB P06746 2/20 0.56
▸ PKM P14618 2/20 0.56
▸ HTT P42858 2/20 0.56
▸ SMN1; SMN2 Q16637 2/20 0.56
▸ NPSR1 Q6W5P4 2/20 0.56
▸ LMNA P02545 1/20 0.56
▸ PRMT1 Q99873 2/20 0.43
▸ PRMT5 O14744 1/20 0.43
▸ CARM1 Q86X55 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12270728 1.00 MAPT (0.56) MAPTMEN1KMT2ATHRBRECQL
SCHEMBL13588290 1.00 MAPT (0.56) MAPTMEN1KMT2ATHRBRECQL
Water SCHEMBL9329059 0.99 MAPT (0.56) MAPTMEN1KMT2ATHRBRECQL
SCHEMBL9664808 0.96 MAPT (0.56) MAPTMEN1KMT2ATHRBRECQL
Water SCHEMBL11530647 0.94 MAPT (0.53) MAPTMEN1KMT2ATHRBRECQL
Pyridine SCHEMBL5078591 0.94 MAPT (0.52) MAPTMEN1KMT2ATHRBRECQL
Pyridine SCHEMBL10522884 0.94 MAPT (0.52) MAPTMEN1KMT2ATHRBRECQL
SCHEMBL9317740 0.92 MAPT (0.55) MAPTMEN1KMT2ATHRBRECQL
SCHEMBL14072247 0.92 MAPT (0.53) MAPTMEN1KMT2ATHRBRECQL
SCHEMBL13653474 0.92 MAPT (0.50) MAPTMEN1KMT2ATHRBRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100239962-A1 TWO-PHOTON ABSORBING OPTICAL RECORDING MATERIAL AND TWO-PHOTON ABSORBING OPTICAL RECORDING AND REPRODUCING METHOD FUJIFILM CORPORATION (JP) 2010-09-23 — — US disclosed
US-20090303855-A1 TWO-PHOTON-ABSORBING RECORDING MEDIUM, TWO-PHOTON-ABSORBING RECORDING/REPRODUCING METHOD, AND TWO-PHOTON-ABSORBING RECORDING/REPRODUCING APPARATUS FUJIFILM CORPORATION (JP) 2009-12-10 — — US disclosed
US-20090051988-A1 HOLOGRAPHIC RECORDING MEDIUM AND HOLOGRAPHIC RECORDING APPARATUS FUJIFILM CORPORATION (JP) 2009-02-26 — — US disclosed
US-7432036-B2 Non-resonant two-photon absorbing material, non-resonant two-photon emitting material, and method for inducing absorption or generating emission of non-resonant two photons by using the material FUJIFILM CORPORATION (JP) 2008-10-07 — — US disclosed
US-7314707-B2 Silver halide photographic emulsion FUJIFILM CORPORATION (JP) 2008-01-01 — — US disclosed
US-7171974-B2 Production method of silver halide photographic emulsion and production apparatus thereof FUJI PHOTO FILM CO., LTD. (JP) 2007-02-06 — — US disclosed
US-7161010-B2 Methine dyes; coloring compound FUJI PHOTO FILM CO., LTD. (JP) 2007-01-09 — — US disclosed
US-7161010-B2 Methine dyes; coloring compound FUJI PHOTO FILM CO., LTD. (JP) 2007-01-09 — — US disclosed
US-20070004923-A1 Methine compound and silver halide photographic material containing the same FUJI PHOTO FILM CO., LTD. 2007-01-04 — — US disclosed
US-5500336-A DYE DESORPTION FUJI PHOTO FILM CO., LTD. (JP) 1996-03-19 — — US disclosed
US-4818670-A Silver halide photographic light-sensitive materials containing compound capable of splitting of diffusible development inhibitor or precursor and silver halide grain having internal fog nucleus KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1989-04-04 — — US disclosed
EP-0233641-A2 Silver halide photographic lightsensitive materials KONICA CORPORATION (JP) 1987-08-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070004923-A1 Methine compound and silver halide photographic material containing the same PYM1, NPM1, METTL3 MAPT 2437/4885MEN1 5/4885KMT2A 96/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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