SCHEMBL8943196

SCHEMBL8943196

CC(=O)Nc1cc(N(CCO)CCO)ccc1N

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 12/20 0.49
HDAC3 O15379 5/20 0.49
HDAC2 Q92769 5/20 0.49
ALDH1A1 P00352 1/20 0.40
TSHR P16473 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
MAPT P10636 2/20 0.37
NPC1 O15118 2/20 0.37
NPSR1 Q6W5P4 1/20 0.37
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
NCOR1 O75376 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
POLB P06746 1/20 0.35
RAB9A P51151 1/20 0.35
S100B P04271 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8379952 0.86 HDAC1 (0.47) HDAC1HDAC3HDAC2ALDH1A1MAPT
SCHEMBL6075087 0.85 S100B (0.51) HDAC1HDAC3HDAC2ALDH1A1TSHR
SCHEMBL22212876 0.85 HDAC1 (0.46) HDAC1HDAC3HDAC2TSHRCA1
SCHEMBL24006345 0.83 HDAC1 (0.45) HDAC1HDAC3HDAC2ALDH1A1MAPT
SCHEMBL15244180 0.83 HDAC1 (0.45) HDAC1HDAC3HDAC2ALDH1A1MAPT
SCHEMBL15071652 0.81 HDAC1 (0.50) HDAC1HDAC3HDAC2MAPTNPC1
SCHEMBL22474129 0.80 HDAC1 (0.47) HDAC1HDAC3HDAC2ALDH1A1TSHR
SCHEMBL9625813 0.80 HDAC1 (0.57) HDAC1HDAC3HDAC2ALDH1A1MAPT
SCHEMBL22476585 0.79 HDAC1 (0.41) HDAC1HDAC3HDAC2TDP1MAPT
SCHEMBL19980976 0.79 HDAC1 (0.41) HDAC1HDAC3HDAC2TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5512414-A ELEMENT CONTAINING MORDANT LAYER FOR BINDING DIFFUSIBLE DYES, LAYER CONTAINING SOLID PARTICLE DISPERSION OF DIFFUSIBLE DYE FORMING COMPOUND, BARRIER LAYER WHICH BLOCKS DIFFUSION OF DYE OUT OF ELEMENT EASTMAN KODAK COMPANY (US) 1996-04-30 US disclosed
US-5512410-A Heat image separation with phenolic thermal solvents and dye releasing couplers EASTMAN KODAK COMPANY (US) 1996-04-30 US disclosed
US-5494775-A DIFFUSION TRANSFER PROCESS FOR COLOR PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1996-02-27 US disclosed
US-5441854-A Photographic image forming process utilizing a barrier layer for diffusible dye containment EASTMAN KODAK COMPANY (US) 1995-08-15 US disclosed
US-5370967-A Polymeric barrier to control diffusion EASTMAN KODAK COMPANY (US) 1994-12-06 US disclosed
US-5360695-A Noncrystallizing EASTMAN KODAK COMPANY (US) 1994-11-01 US disclosed
US-5356750-A Dye releasing couplers for heat image separation systems EASTMAN KODAK COMPANY (US) 1994-10-18 US disclosed
US-5342730-A With mordant and stripping layers EASTMAN KODAK COMPANY (US) 1994-08-30 US disclosed
EP-0608825-A1 Solid particle thermal solvent dispersions EASTMAN KODAK COMPANY (US) 1994-08-03 EP disclosed
US-5322758-A Integral color diffusion transfer element for large volume development EASTMAN KODAK COMPANY (US) 1994-06-21 US disclosed
EP-0590567-A1 Integral color diffusion transfer element for large volume development EASTMAN KODAK COMPANY (US) 1994-04-06 EP disclosed
EP-0590566-A1 Barrier layer for dye containment in photographic elements EASTMAN KODAK COMPANY (US) 1994-04-06 EP disclosed
EP-0590565-A1 Image separation system for large volume development EASTMAN KODAK COMPANY (US) 1994-04-06 EP disclosed
US-5288745-A Diffusion transfer for color photography; polymeric mordant dye barrier layers EASTMAN KODAK COMPANY (US) 1994-02-22 US disclosed
US-4178182-A ACRYLIC ESTER OF POLYOL USED AS POLYMERIZED INTERLAYER OR OVERCOAT, STORAGE STABILITY FUJI PHOTO FILM CO., LTD (JP) 1979-12-11 US disclosed
US-4110355-A COLOR COUPLERS POLAROID CORPORATION (US) 1978-08-29 US disclosed