Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19980985 | 0.96 | HDAC1 (0.38) | HDAC1HDAC2HDAC3TSHR | |
| SCHEMBL19981012 | 0.85 | HDAC1 (0.33) | HDAC1HDAC2TDP1POLBAPEX1 | |
| SCHEMBL19980897 | 0.85 | HDAC1 (0.40) | HDAC1HDAC2HDAC3CA1CA2 | |
| SCHEMBL19980987 | 0.84 | MTNR1B (0.35) | HDAC1HDAC2HDAC3POLB | |
| SCHEMBL22212876 | 0.84 | HDAC1 (0.46) | HDAC1HDAC2HDAC3CA1CA2 | |
| SCHEMBL19980979 | 0.83 | S100B (0.48) | TDP1POLBAPEX1HTTCA1 | |
| SCHEMBL19980998 | 0.82 | POLB (0.30) | TDP1POLBAPEX1HTT | |
| SCHEMBL19980955 | 0.80 | HDAC1 (0.38) | HDAC1HDAC2HDAC3TDP1POLB | |
| SCHEMBL8943196 | 0.79 | HDAC1 (0.49) | HDAC1HDAC2HDAC3TDP1POLB | |
| SCHEMBL19903994 | 0.78 | TSHR (0.35) | HDAC1HDAC2HDAC3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601268-B1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2018-03-21 | — | — | EP | disclosed |