Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | CTSG | P08311 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8943219 | 1.00 | TRPA1 (0.44) | TRPA1TYRELANECTSGPPARG | |
| SCHEMBL27581602 | 0.89 | TRPA1 (0.56) | TRPA1ALDH1A1MAPK1TSHRKDM4E | |
| SCHEMBL7876621 | 0.76 | TRPA1 (0.76) | TRPA1TYRALDH1A1MAPK1TSHR | |
| SCHEMBL7788343 | 0.74 | TYR (0.51) | TRPA1TYRPPARGALDH1A1TSHR | |
| SCHEMBL7788402 | 0.74 | TYR (0.51) | TRPA1TYRPPARGALDH1A1TSHR | |
| SCHEMBL6424905 | 0.74 | TYR (0.51) | TYRELANECTSGALDH1A1CES2 | |
| SCHEMBL17552282 | 0.73 | TRPA1 (0.62) | TRPA1ELANECTSGALDH1A1MAPK1 | |
| SCHEMBL3763234 | 0.73 | TRPA1 (0.62) | TRPA1ELANECTSGALDH1A1MAPK1 | |
| SCHEMBL3763236 | 0.73 | TRPA1 (0.62) | TRPA1ELANECTSGALDH1A1MAPK1 | |
| SCHEMBL28740970 | 0.70 | ELANE (0.60) | TYRELANECTSGPPARGTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8176135-A | — | — | None | — | — | JP | disclosed |
| JP-H08176135-A | NEW PHTHALIDE DERIVATIVE AND SUPPRESSING AGENT OF CELL PROLIFERATION CONTAINING THE SAME | TSUMURA & CO | 1996-07-09 | — | — | JP | disclosed |