Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 4/20 | 0.40 |
| ▸ | CTSG | P08311 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17552282 | 1.00 | TRPA1 (0.62) | TRPA1ALDH1A1MAPK1TSHRMAOA | |
| SCHEMBL3763234 | 1.00 | TRPA1 (0.62) | TRPA1ALDH1A1MAPK1TSHRMAOA | |
| SCHEMBL3751329 | 0.88 | TRPA1 (0.62) | TRPA1ALDH1A1MAPK1TSHRMAOA | |
| SCHEMBL29466168 | 0.88 | TRPA1 (0.62) | TRPA1ALDH1A1MAPK1TSHRMAOA | |
| SCHEMBL3751327 | 0.88 | TRPA1 (0.62) | TRPA1ALDH1A1MAPK1TSHRMAOA | |
| SCHEMBL11967649 | 0.88 | TRPA1 (0.62) | TRPA1ALDH1A1MAPK1TSHRMAOA | |
| SCHEMBL27581602 | 0.84 | TRPA1 (0.56) | TRPA1ALDH1A1MAPK1TSHRMAOA | |
| SCHEMBL29466170 | 0.80 | TRPA1 (0.46) | TRPA1ALDH1A1MAPK1TSHRMAOA | |
| Z-Butylidenephthalide SCHEMBL290483 | 0.77 | TRPA1 (1.00) | TRPA1ALDH1A1MAPK1TSHRHPGD | |
| Z-Butylidenephthalide SCHEMBL290482 | 0.77 | TRPA1 (1.00) | TRPA1ALDH1A1MAPK1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1993580-A1 | COMBINATION THERAPY FOR TREATMENT OF PATIENTS WITH NEUROLOGICAL DISORDERS AND CEREBRAL INFARCTION | Moleac Pte Ltd. (SG) | 2008-11-26 | — | — | EP | claimed |
| WO-2007106049-A1 | COMBINATION THERAPY FOR TREATMENT OF PATIENTS WITH NEUROLOGICAL DISORDERS AND CEREBRAL INFARCTION | MOLEAC PTE LTD (SG) | 2007-09-20 | — | — | WO | claimed |
| CN-115814004-A | Medicine composition for treating bone disease | 北京朕荣国际生物科技有限公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-115737732-A | Medicine composition for treating compact osteitis | 北京朕荣国际生物科技有限公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-112168890-A | Formula and preparation method of quick-acting rescue crude drug for rescuing diseased and dangerous fishes | 王虎 | 2021-01-05 | — | — | CN | disclosed |
| EP-2508191-A1 | Combination therapy for treatment of patients with neurological disorders and cerebral infarction | Moleac Pte Ltd. (SG) | 2012-10-10 | — | — | EP | disclosed |
| US-7846967-B2 | Cosmetic composition for skin whitening comprising senkyunolide A as active ingredient | COREANA COSMETICS CO., LTD. (KR) | 2010-12-07 | — | — | US | disclosed |
| US-20090162459-A1 | Combination Therapy for Treatment of Patients with Neurological Disorders and Cerebral Infarction | MOLEAC PTE. LTD (SG) | 2009-06-25 | — | — | US | disclosed |
| EP-1993580-A1 | COMBINATION THERAPY FOR TREATMENT OF PATIENTS WITH NEUROLOGICAL DISORDERS AND CEREBRAL INFARCTION | Moleac Pte Ltd. (SG) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007106049-A1 | COMBINATION THERAPY FOR TREATMENT OF PATIENTS WITH NEUROLOGICAL DISORDERS AND CEREBRAL INFARCTION | MOLEAC PTE LTD (SG) | 2007-09-20 | — | — | WO | disclosed |
| US-20060165619-A1 | Cosmetic composition for skin whitening comprising senkyunolide A as active ingredient | COREANA COSMETICS CO., LTD. (KR) | 2006-07-27 | — | — | US | disclosed |
| US-20040081631-A1 | Cosmetic composition for skin whitening comprising senkyunolide a as active ingredient | COREANA COSMETICS CO., LTD. (KR) | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060165619-A1 | Cosmetic composition for skin whitening comprising senkyunolide A as active ingredient | MC1R, CLK3, WNK1 | TRPA1 2631/4885ALDH1A1 3425/4885MAPK1 1689/4885 |
| US-20040081631-A1 | Cosmetic composition for skin whitening comprising senkyunolide a as active ingredient | MC1R, CLK3, WNK1 | TRPA1 2631/4885ALDH1A1 3425/4885MAPK1 1689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.