Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | FDPS | P14324 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21195142 | 1.00 | LMNA (0.34) | LMNAFDPSALDH1A1HSD17B10MEN1 | |
| SCHEMBL21195153 | 1.00 | LMNA (0.34) | LMNAFDPSALDH1A1HSD17B10MEN1 | |
| SCHEMBL8430779 | 1.00 | LMNA (0.34) | LMNAFDPSALDH1A1HSD17B10MEN1 | |
| SCHEMBL487261 | 0.92 | CNR1 (0.34) | ALDH1A1 | |
| SCHEMBL28218465 | 0.89 | LMNA (0.39) | LMNAFDPSCYP2D6SPHK1GMNN | |
| SCHEMBL28308350 | 0.89 | LMNA (0.39) | LMNAFDPSCYP2D6SPHK1GMNN | |
| SCHEMBL28308352 | 0.89 | LMNA (0.39) | LMNAFDPSCYP2D6SPHK1GMNN | |
| SCHEMBL21494272 | 0.89 | LMNA (0.39) | LMNAFDPSCYP2D6SPHK1GMNN | |
| SCHEMBL28068686 | 0.83 | DHPS (0.33) | — | |
| SCHEMBL8432548 | 0.82 | LMNA (0.33) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489375-A | HYDROTREATING MIXTURE OF HYDROCARBONACEOUS FEEDSTOCK, SOLUBLE 2,4-HETEROATOM SUBSTITUTED-MOLYBDENA-3,3-DIOXOCYCLOPENTANE CATALYST | AMOCO CORPORATION (US) | 1996-02-06 | — | — | US | disclosed |
| US-5446002-A | 2,4-heteroatom substituted-molybdena-3,3-dioxacyclopentane compound hydrorefining catalysts | AMOCO CORPORATION (US) | 1995-08-29 | — | — | US | disclosed |
| US-5412130-A | Method for preparation of organic molybdenum compounds | R. T. VANDERBILT COMPANY, INC. (US) | 1995-05-02 | — | — | US | disclosed |