SCHEMBL8943391

SCHEMBL8943391

CCCCCCCCOc1ccc(O)c(-c2ccccc2O)c1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTPN11 Q06124 2/20 0.56
NR5A1 Q13285 1/20 0.54
PDK2 Q15119 3/20 0.52
TSHR P16473 2/20 0.49
LTA4H P09960 2/20 0.49
MEN1 O00255 1/20 0.48
NPC1 O15118 1/20 0.48
ALDH1A1 P00352 1/20 0.48
GAA P10253 1/20 0.48
MAPT P10636 1/20 0.48
RAB9A P51151 1/20 0.48
KMT2A Q03164 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
CNR2 P34972 2/20 0.46
PTPN1 P18031 1/20 0.46
PLA2G4B P0C869 1/20 0.46
TP53 P04637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9170976 1.00 PTPN11 (0.56) PTPN11NR5A1PDK2TSHRLTA4H
SCHEMBL9735320 1.00 PTPN11 (0.56) PTPN11NR5A1PDK2TSHRLTA4H
SCHEMBL9333938 1.00 PTPN11 (0.56) PTPN11NR5A1PDK2TSHRLTA4H
SCHEMBL6866588 0.87 HDAC8 (0.55) PTPN11NR5A1PDK2LTA4HCNR2
SCHEMBL10416929 0.85 MEN1 (0.43) PTPN11NR5A1PDK2LTA4HMEN1
SCHEMBL11551593 0.83 PTPN11 (0.54) PTPN11PDK2MEN1NPC1ALDH1A1
SCHEMBL8940667 0.82 NR5A1 (0.51) NR5A1LTA4HMEN1NPC1ALDH1A1
SCHEMBL7922315 0.82 PTPN11 (0.55) PTPN11NR5A1TSHRLTA4HPTPN1
SCHEMBL14892810 0.81 PTPN11 (0.50) PTPN11NR5A1PDK2TSHRALDH1A1
SCHEMBL30154513 0.81 PTPN11 (0.50) PTPN11NR5A1PDK2TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0467721-B1 Optically active compound having a delta- valerolactone ring and liquid crystal composition containing same MITSUBISHI RAYON CO (JP) 1996-03-27 EP disclosed
US-5480580-A COMPOUNDS FOR VISUAL AIDS WITH GOOD STABILITY MITSUBISHI RAYON COMPANY LTD. (JP) 1996-01-02 US disclosed
EP-0316011-B1 Mesomorphic compound and liquid crystal composition containing same CANON KK (JP) 1994-04-06 EP disclosed
US-5149462-A Used as ferroelectric liquid crystal MITSUBISHI RAYON COMPANY LTD. (JP) 1992-09-22 US disclosed
EP-0467721-A1 Optically active compound having a delta- valerolactone ring and liquid crystal composition containing same MITSUBISHI RAYON CO., LTD (JP) 1992-01-22 EP disclosed
US-5075031-A Prevent reverse domain CANON KABUSHIKI KAISHA (JP) 1991-12-24 US disclosed
EP-0409066-A2 Optically active compound for liquid crystal and its use MITSUBISHI RAYON COMPANY, LTD. (JP) 1991-01-23 EP disclosed
US-4959173-A Optically active ester compound ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1990-09-25 US disclosed
EP-0316011-A2 Mesomorphic compound and liquid crystal composition containing same CANON KABUSHIKI KAISHA (JP) 1989-05-17 EP disclosed