Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 2/20 | 0.56 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.54 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | LTA4H | P09960 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9170976 | 1.00 | PTPN11 (0.56) | PTPN11NR5A1PDK2TSHRLTA4H | |
| SCHEMBL8943391 | 1.00 | PTPN11 (0.56) | PTPN11NR5A1PDK2TSHRLTA4H | |
| SCHEMBL9333938 | 1.00 | PTPN11 (0.56) | PTPN11NR5A1PDK2TSHRLTA4H | |
| SCHEMBL6866588 | 0.87 | HDAC8 (0.55) | PTPN11NR5A1PDK2LTA4HCNR2 | |
| SCHEMBL10416929 | 0.85 | MEN1 (0.43) | PTPN11NR5A1PDK2LTA4HMEN1 | |
| SCHEMBL11551593 | 0.83 | PTPN11 (0.54) | PTPN11PDK2MEN1NPC1ALDH1A1 | |
| SCHEMBL8940667 | 0.82 | NR5A1 (0.51) | NR5A1LTA4HMEN1NPC1ALDH1A1 | |
| SCHEMBL7922315 | 0.82 | PTPN11 (0.55) | PTPN11NR5A1TSHRLTA4HPTPN1 | |
| SCHEMBL14892810 | 0.81 | PTPN11 (0.50) | PTPN11NR5A1PDK2TSHRALDH1A1 | |
| SCHEMBL30154513 | 0.81 | PTPN11 (0.50) | PTPN11NR5A1PDK2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098599-A | Aromatic esters with sulfide groups as liquid crystals | MITSUBISHI RAYON COMPANY LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0354355-A1 | Optically active compound and liquid crystal composition | MITSUBISHI RAYON CO., LTD. (JP) | 1990-02-14 | — | — | EP | disclosed |