Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.51 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8940719 | 0.92 | NR5A1 (0.49) | NR5A1THRATHRBPLA2G4BMEN1 | |
| SCHEMBL9333938 | 0.82 | PTPN11 (0.56) | NR5A1PLA2G4BMEN1NPC1ALDH1A1 | |
| SCHEMBL9735320 | 0.82 | PTPN11 (0.56) | NR5A1PLA2G4BMEN1NPC1ALDH1A1 | |
| SCHEMBL8943391 | 0.82 | PTPN11 (0.56) | NR5A1PLA2G4BMEN1NPC1ALDH1A1 | |
| SCHEMBL9170976 | 0.82 | PTPN11 (0.56) | NR5A1PLA2G4BMEN1NPC1ALDH1A1 | |
| SCHEMBL16314448 | 0.80 | THRA (0.56) | NR5A1THRATHRBPLA2G4BSMPD1 | |
| SCHEMBL25759920 | 0.80 | MAOB (0.50) | NR5A1THRATHRBLTA4H | |
| SCHEMBL2091707 | 0.79 | NR5A1 (0.61) | NR5A1THRATHRBPLA2G4BLTA4H | |
| SCHEMBL4963096 | 0.79 | NR5A1 (0.66) | NR5A1PLA2G4BMEN1NPC1ALDH1A1 | |
| SCHEMBL4963128 | 0.79 | NR5A1 (0.66) | NR5A1PLA2G4BMEN1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700384-A1 | PROCESS FOR PREPARING AND RESOLVING 2-PHENYL-3-AMINOPIPERIDINE | PFIZER (US) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994027966-A1 | PROCESS FOR PREPARING AND RESOLVING 2-PHENYL-3-AMINOPIPERIDINE | PFIZER INC. (US) | 1994-12-08 | — | — | WO | disclosed |
| EP-0581777-A1 | STEREOSELECTIVE PREPARATION OF SUBSTITUTED PIPERIDINES | PFIZER INC. (US) | 1994-02-09 | — | — | EP | disclosed |
| WO-1992017449-A1 | STEREOSELECTIVE PREPARATION OF SUBSTITUTED PIPERIDINES | PFIZER INC. (US) | 1992-10-15 | — | — | WO | disclosed |