Bisphenol A

Bisphenol A

SCHEMBL8943594

CC(C)(c1ccc(O)cc1)c1ccc(O)cc1.O=C(Cl)c1ccc(C(=O)Cl)cc1.O=C(Cl)c1cccc(C(=O)Cl)c1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.56
ESR2 Q92731 5/20 0.56
ESRRG P62508 5/20 0.52
CYP3A4 P08684 3/20 0.52
TSHR P16473 2/20 0.52
AR P10275 1/20 0.52
HPGD P15428 1/20 0.52
SLC6A2 P23975 1/20 0.52
SLC6A4 P31645 1/20 0.52
HTR6 P50406 1/20 0.52
SLC6A3 Q01959 1/20 0.52
HSD17B10 Q99714 1/20 0.52
ALDH1A1 P00352 3/20 0.50
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ESRRB O95718 1/20 0.39
CES2 O00748 1/20 0.39
LMNA P02545 2/20 0.38
TYR P14679 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bisphenol A SCHEMBL5682512 0.98 ESR1 (0.54) ESR1ESR2ESRRGCYP3A4TSHR
Bisphenol A SCHEMBL7906361 0.90 ESR1 (0.64) ESR1ESR2ESRRGCYP3A4TSHR
SCHEMBL11138232 0.84 KCNK9 (0.57) MEN1KMT2ASMN1; SMN2LMNAKCNK9
SCHEMBL11137047 0.82 ESR1 (0.44) ESR1ESR2ESRRGCYP3A4TSHR
SCHEMBL7718602 0.82 ESR1 (0.48) ESR1ESR2ESRRGCYP3A4TSHR
Bisphenol A SCHEMBL7055240 0.82 ESR1 (0.58) ESR1ESR2ESRRGCYP3A4TSHR
Bisphenol A SCHEMBL9246479 0.82 ESR1 (0.58) ESR1ESR2ESRRGCYP3A4TSHR
Bisphenol A SCHEMBL11199980 0.81 ESR1 (0.61) ESR1ESR2ESRRGCYP3A4TSHR
Bisphenol A SCHEMBL11051136 0.81 ESR1 (0.56) ESR1ESR2ESRRGCYP3A4TSHR
SCHEMBL11138148 0.79 HDAC8 (0.54) ESR1ESR2ESRRGCYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5506330-A INTERFACIAL POLYMERIZATION OF AROMATIC POLYESTER COPOLYMER KOREA KUMBO PETROCHEMICAL CO., LTD. (KR) 1996-04-09 US disclosed
EP-0158733-A1 Polyestercarbonate/polyetherimide blends GENERAL ELECTRIC COMPANY (US) 1985-10-23 EP disclosed