SCHEMBL7718602

SCHEMBL7718602

CC(C)(c1ccc(C(=O)Cl)cc1)c1ccc(C(=O)Cl)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.48
ESR2 Q92731 3/20 0.48
CYP3A4 P08684 2/20 0.48
HPGD P15428 2/20 0.48
AR P10275 1/20 0.48
TSHR P16473 1/20 0.48
SLC6A2 P23975 1/20 0.48
SLC6A4 P31645 1/20 0.48
HTR6 P50406 1/20 0.48
ESRRG P62508 1/20 0.48
SLC6A3 Q01959 1/20 0.48
HSD17B10 Q99714 1/20 0.48
ALDH1A1 P00352 4/20 0.43
HDAC1 Q13547 1/20 0.43
POLB P06746 1/20 0.42
SRD5A2 P31213 1/20 0.42
RXRA P19793 1/20 0.41
RXRB P28702 1/20 0.41
NPC1 O15118 5/20 0.39
RAB9A P51151 5/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bisphenol A SCHEMBL7906361 0.92 ESR1 (0.64) ESR1ESR2CYP3A4HPGDAR
SCHEMBL259824 0.88 HPGD (0.48) ESR1ESR2CYP3A4HPGDAR
SCHEMBL38841 0.86 HDAC1 (0.59) HSD17B10ALDH1A1HDAC1POLBSRD5A2
SCHEMBL27704404 0.84 ALDH1A1 (0.42) ALDH1A1HDAC1POLBSRD5A2NPC1
SCHEMBL13207522 0.82 KLF10 (0.41) ESR1ESR2CYP3A4HPGDAR
SCHEMBL10036585 0.82 RXRA (0.47) ESR1ESR2CYP3A4HPGDAR
Bisphenol A SCHEMBL8943594 0.82 ESR1 (0.56) ESR1ESR2CYP3A4HPGDAR
SCHEMBL106525 0.82 CES2 (0.45) ALDH1A1HDAC1POLBSRD5A2NPC1
SCHEMBL4114080 0.82 CES2 (0.45) ALDH1A1HDAC1POLBSRD5A2NPC1
Bisphenol A SCHEMBL5682512 0.81 ESR1 (0.54) ESR1ESR2CYP3A4HPGDAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120305484-A1 Thermally Rearranged (TR) Polymers as Membranes for Ethanol Dehydration BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2012-12-06 US claimed
WO-2012166153-A1 THERMALLY REARRANGED (TR) POLYMERS AS MEMBRANES FOR ETHANOL DEHYDRATION BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMS (US) 2012-12-06 WO claimed
CN-115428128-A Hollow microspheres 株式会社德山 2022-12-02 CN disclosed
US-10654002-B2 Thin film composite forward osmosis membranes with performance enhancing layers INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2020-05-19 US disclosed
US-20190300472-A1 POLYMERIZABLE MONOMER, METHOD OF PRODUCING POLYMERIZABLE MONOMER, CURABLE COMPOSITION AND RESIN MEMBER TOKUYAMA DENTAL CORPORATION (JP) 2019-10-03 US disclosed
US-10384172-B2 Composite membrane with multi-layered active layer INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2019-08-20 US disclosed
US-10301430-B2 Bis(azobenzene) diamines and photomechanical polymers made therefrom THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2019-05-28 US disclosed
US-10294255-B1 Multifunctional crosslinking agent, crosslinked polymer, and method of making same THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2019-05-21 US disclosed
US-10293308-B2 Antifouling and antimicrobial coatings for thin film composite membranes INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2019-05-21 US disclosed
US-20190015789-A1 ANTIFOULING AND ANTIMICROBIAL COATINGS FOR THIN FILM COMPOSITE MEMBRANES INTERNATIONAL BUSINESS MACHINES CORPORATION 2019-01-17 US disclosed
US-10005042-B2 Thin film composite forward osmosis membranes with performance enhancing layers INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-06-26 US disclosed
EP-0414066-A2 Polyesters and polyestercarbonates BAYER AG (DE) 1991-02-27 EP disclosed
EP-0414062-A2 Process for preparing aromatic dicarboxylic acids and novel aromatic dicarboxylic acids BAYER AG (DE) 1991-02-27 EP disclosed
EP-0399000-A1 LOW DIELECTRIC FLUORINATED POLY(PHENYLENE ETHER KETONE) FILM AND COATING. US HEALTH (US) 1990-11-28 EP disclosed
US-4960835-A ENGINEERING THERMOPLASTICS RAYCHEM LIMITED (GB) 1990-10-02 US disclosed
US-4918153-A Copoly(imidine-amide) NIPPON STEEL CHEMICAL CO., LTD. (JP) 1990-04-17 US disclosed
US-4845179-A CONDENSATION POLYMERIZATION RAYCHEM LIMITED (GB) 1989-07-04 US disclosed
US-4564705-A POLYAMIDE, POLYUREA AND POLYURETHANE MONOMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-01-14 US disclosed
EP-0154506-A2 Preparation of organic polymers RAYCHEM LIMITED (GB) 1985-09-11 EP disclosed
US-4451642-A Bis(aminoneopentyl) aromatics and polyamides derived therefrom E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-05-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10301430-B2 Bis(azobenzene) diamines and photomechanical polymers made therefrom WASF2, PBRM1, WEE1 ESR1 2481/4885ESR2 3659/4885CYP3A4 3214/4885
US-20190300472-A1 POLYMERIZABLE MONOMER, METHOD OF PRODUCING POLYMERIZABLE MONOMER, CURABLE COMPOSITION AND RESIN MEMBER CHRM1, CHRM2, H1-0 ESR1 797/4885ESR2 1354/4885CYP3A4 2495/4885
US-10294255-B1 Multifunctional crosslinking agent, crosslinked polymer, and method of making same PARN, PAICS, PAM ESR1 4181/4885ESR2 3767/4885CYP3A4 4347/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.