Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.64 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.64 |
| ▸ | ESRRG | P62508 | 5/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | AR | P10275 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.64 |
| ▸ | HTR6 | P50406 | 1/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TYR | P14679 | 2/20 | 0.46 |
| ▸ | ESRRB | O95718 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7718602 | 0.92 | ESR1 (0.48) | ESR1ESR2ESRRGCYP3A4HPGD | |
| Bisphenol A SCHEMBL8943594 | 0.90 | ESR1 (0.56) | ESR1ESR2ESRRGCYP3A4HPGD | |
| Bisphenol A SCHEMBL5682512 | 0.88 | ESR1 (0.54) | ESR1ESR2ESRRGCYP3A4HPGD | |
| SCHEMBL11138094 | 0.87 | NPC1 (0.55) | ESR1ESR2ESRRGCYP3A4HPGD | |
| Bisphenol A SCHEMBL6581820 | 0.85 | ESR1 (0.73) | ESR1ESR2ESRRGCYP3A4HPGD | |
| Bisphenol A SCHEMBL3295660 | 0.85 | ESR1 (0.73) | ESR1ESR2ESRRGCYP3A4HPGD | |
| SCHEMBL11133866 | 0.84 | NR1H4 (0.49) | ESR1ESR2ESRRGCYP3A4HPGD | |
| SCHEMBL1454951 | 0.82 | LMNA (0.60) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| Hydroquinone SCHEMBL7948998 | 0.82 | LMNA (0.60) | ESR1ESR2CYP3A4HPGDHSD17B10 | |
| SCHEMBL2689876 | 0.82 | ESR1 (0.67) | ESR1ESR2ESRRGCYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0013761-A1 | Process for preparing poly(ester-carbonates) from dicarboxylic acid chlorides | ALLIED CORPORATION (US) | 1980-08-06 | — | — | EP | claimed |
| US-4194038-A | TERTIARY AMINE CATALYST | ALLIED CHEMICAL CORPORATION (US) | 1980-03-18 | — | — | US | claimed |
| US-6194487-B1 | EXPOSURE OF PARTICLES TO SUPERSATURATED VAPOR OF MONOMERS, CONDENSATION AND POLYMERIZATION ON THE SURFACE | SHARP KABUSHIKI KAISHA (JP) | 2001-02-27 | — | — | US | disclosed |