SCHEMBL8943645

SCHEMBL8943645

Cc1ccc(N(c2ccc(C)cc2)c2ccc(Sc3ccc(N(c4ccc(C)cc4)c4ccc(C)cc4)cc3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
TSHR P16473 3/20 0.46
MLYCD O95822 1/20 0.44
TDP1 Q9NUW8 2/20 0.41
HKDC1 Q2TB90 2/20 0.41
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
KMT2A Q03164 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ACHE P22303 1/20 0.40
PTGIR P43119 1/20 0.40
HAO1 Q9UJM8 1/20 0.39
MCL1 Q07820 2/20 0.39
BCL2 P10415 1/20 0.39
MMP2 P08253 1/20 0.39
MMP9 P14780 1/20 0.39
HPGD P15428 1/20 0.38
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24133973 1.00 ALDH1A1 (0.46) ALDH1A1TSHRMLYCDTDP1HKDC1
SCHEMBL24134022 0.91 ALDH1A1 (0.44) ALDH1A1TSHRMLYCDTDP1HKDC1
SCHEMBL8944073 0.91 ALDH1A1 (0.45) ALDH1A1TSHRMLYCDTDP1HKDC1
SCHEMBL8944197 0.86 ACHE (0.56) ALDH1A1MAPTNPSR1ACHEPTGIR
SCHEMBL19418359 0.86 TSHR (0.56) ALDH1A1TSHRMLYCDTDP1HKDC1
SCHEMBL7486403 0.84 ALDH1A1 (0.61) ALDH1A1TSHRTDP1MAPTL3MBTL1
SCHEMBL83853 0.84 ACHE (0.57) ALDH1A1TSHRMLYCDTDP1HKDC1
SCHEMBL12245875 0.84 ACHE (0.57) ALDH1A1TSHRMLYCDTDP1HKDC1
SCHEMBL16982395 0.84 ALDH1A1 (0.61) ALDH1A1TSHRTDP1MAPTL3MBTL1
SCHEMBL6123161 0.84 ALDH1A1 (0.61) ALDH1A1TSHRTDP1MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed