Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | RAF1 | P04049 | 1/20 | 0.64 |
| ▸ | GFER | P55789 | 1/20 | 0.64 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | PRKDC | P78527 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7391355 | 0.88 | MAPT (0.50) | MAPTMAPK1ALDH1A1LMNAHPGD | |
| SCHEMBL7391611 | 0.85 | MAPT (0.58) | MAPTMAPK1ALDH1A1LMNAHPGD | |
| SCHEMBL7390018 | 0.85 | ABCC3 (0.56) | MAPTMAPK1ALDH1A1LMNAHPGD | |
| SCHEMBL3364760 | 0.83 | MAPK1 (0.64) | MAPTMAPK1ALDH1A1POLBERN1 | |
| SCHEMBL1161468 | 0.82 | ALDH1A1 (0.60) | MAPTMAPK1ALDH1A1LMNAMEN1 | |
| SCHEMBL30766429 | 0.82 | ALDH1A1 (0.60) | MAPTMAPK1ALDH1A1LMNAMEN1 | |
| SCHEMBL7287497 | 0.82 | MAPT (0.50) | MAPTMAPK1ALDH1A1LMNAHPGD | |
| SCHEMBL5151922 | 0.82 | MAPT (0.68) | MAPTMAPK1ALDH1A1LMNAHPGD | |
| SCHEMBL7392802 | 0.82 | TTR (0.56) | MAPTMAPK1ALDH1A1LMNAHPGD | |
| SCHEMBL30639026 | 0.81 | MAPT (0.67) | MAPTMAPK1ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541325-A | ENZYME INHIBITORS, ANTIALLERGENS | JANSSEN PHARMACEUTICA N.V. (BE) | 1996-07-30 | — | — | US | disclosed |