SCHEMBL8943716

SCHEMBL8943716

Cc1cccc(N(c2cccc(C)c2)c2ccccc2N(c2cccc(C)c2)c2cccc(C)c2)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 5/20 0.48
SIGMAR1 Q99720 2/20 0.40
ALDH1A1 P00352 2/20 0.39
MAPK1 P28482 2/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
JAK2 O60674 1/20 0.39
HTT P42858 1/20 0.39
PAX8 Q06710 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
HSD17B1 P14061 2/20 0.39
HSD17B2 P37059 2/20 0.39
LMNA P02545 3/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2C9 P11712 2/20 0.38
CYP2C19 P33261 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
RECQL P46063 1/20 0.38
NR1I2 O75469 1/20 0.38
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29733508 0.96 ACHE (0.44) ACHESIGMAR1ALDH1A1MAPK1NPC1
SCHEMBL331098 0.96 ACHE (0.44) ACHESIGMAR1ALDH1A1MAPK1NPC1
SCHEMBL30242039 0.96 ACHE (0.44) ACHESIGMAR1ALDH1A1MAPK1NPC1
SCHEMBL28775867 0.94 ACHE (0.42) ACHESIGMAR1ALDH1A1MAPK1NPC1
SCHEMBL31651413 0.94 ACHE (0.42) ACHESIGMAR1ALDH1A1MAPK1NPC1
SCHEMBL4110376 0.89 HSD17B1 (0.42) ACHESIGMAR1ALDH1A1NPC1RAB9A
SCHEMBL21816961 0.86 ACHE (0.39) ACHESIGMAR1ALDH1A1MAPK1NPC1
SCHEMBL3877943 0.86 ACHE (0.39) ACHESIGMAR1ALDH1A1MAPK1NPC1
SCHEMBL977663 0.85 ACHE (0.58) ACHESIGMAR1ALDH1A1MAPK1NPC1
SCHEMBL10128581 0.85 ACHE (0.42) ACHESIGMAR1ALDH1A1MAPK1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2291479-B1 ADHESIVE ENCAPSULATING COMPOSITION AND ELECTRONIC DEVICES MADE THEREWITH 3M INNOVATIVE PROPERTIES CO (US) 2013-05-22 EP disclosed
US-5494765-A Electrophotosensitive material using a phenylenediamine derivative MITA INDUSTRIAL CO. LTD (JP) 1996-02-27 US disclosed