SCHEMBL8943783

SCHEMBL8943783

COc1cccc(N(c2ccccc2)c2ccc(Oc3ccc(N(c4ccccc4)c4cccc(OC)c4)cc3)cc2)c1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.57
PGR P06401 7/20 0.55
HSD17B1 P14061 1/20 0.52
HSD17B2 P37059 1/20 0.52
SMN1; SMN2 Q16637 2/20 0.50
CETP P11597 1/20 0.45
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
HTT P42858 1/20 0.44
MTNR1A P48039 2/20 0.43
MTNR1B P49286 2/20 0.43
NTRK1 P04629 1/20 0.43
IGF1R P08069 1/20 0.43
FGFR1 P11362 1/20 0.43
NTRK2 Q16620 1/20 0.43
CA4 P22748 1/20 0.43
NR3C1 P04150 1/20 0.43
ALOX15 P16050 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8943967 0.96 HSD17B1 (0.55) LTA4HPGRHSD17B1HSD17B2SMN1; SMN2
SCHEMBL13385303 0.93 CA4 (0.52) LTA4HPGRHSD17B1HSD17B2KDM4E
SCHEMBL10065629 0.93 CA4 (0.50) PGRHSD17B1HSD17B2ALDH1A1MTNR1A
SCHEMBL10066011 0.93 CA4 (0.50) PGRHSD17B1HSD17B2ALDH1A1MTNR1A
SCHEMBL8820063 0.93 CA4 (0.50) PGRHSD17B1HSD17B2ALDH1A1MTNR1A
SCHEMBL10066025 0.91 CA4 (0.48) PGRHSD17B1HSD17B2ALDH1A1MTNR1A
SCHEMBL20386564 0.91 CA4 (0.52) LTA4HHSD17B1HSD17B2ALDH1A1MTNR1A
SCHEMBL1134073 0.91 CA4 (0.52) LTA4HHSD17B1HSD17B2ALDH1A1MTNR1A
SCHEMBL8943776 0.90 HSD17B1 (0.50) LTA4HPGRHSD17B1HSD17B2SMN1; SMN2
SCHEMBL8944301 0.89 HSD17B1 (0.51) LTA4HPGRHSD17B1HSD17B2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed