SCHEMBL1134073

SCHEMBL1134073

COc1cccc(N(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.52
MTNR1A P48039 4/20 0.49
MTNR1B P49286 4/20 0.49
ACHE P22303 1/20 0.48
ALOX15 P16050 1/20 0.47
MAOB P27338 1/20 0.47
ENPP2 Q13822 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
ALDH1A1 P00352 1/20 0.47
CYP3A4 P08684 1/20 0.47
HSD17B2 P37059 3/20 0.46
HSD17B1 P14061 2/20 0.46
LTA4H P09960 1/20 0.45
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
ESR1 P03372 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20386564 1.00 CA4 (0.52) CA4MTNR1AMTNR1BACHEALOX15
SCHEMBL8820063 0.98 CA4 (0.50) CA4MTNR1AMTNR1BACHEALOX15
SCHEMBL10066011 0.98 CA4 (0.50) CA4MTNR1AMTNR1BACHEALOX15
SCHEMBL10065629 0.98 CA4 (0.50) CA4MTNR1AMTNR1BACHEALOX15
SCHEMBL10066025 0.96 CA4 (0.48) CA4MTNR1AMTNR1BACHEALOX15
SCHEMBL13385303 0.94 CA4 (0.52) CA4MTNR1AMTNR1BACHEALOX15
SCHEMBL14163837 0.94 ACHE (0.50) MTNR1AMTNR1BACHEALOX15ENPP2
SCHEMBL31256052 0.94 ACHE (0.54) CA4MTNR1AMTNR1BACHEALOX15
SCHEMBL20979821 0.94 ACHE (0.54) CA4MTNR1AMTNR1BACHEALOX15
SCHEMBL914300 0.93 CA4 (0.45) CA4MTNR1AMTNR1BACHEALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118593720-A Biotin receptor targeted glutathione-responsive photodynamic therapy-chemotherapy combined drug and preparation method and application thereof 徐州医科大学 2024-09-06 CN claimed
CN-114989081-B Colorimetric probe and preparation method and application thereof 南华大学 2023-06-13 CN claimed
CN-118593720-A Biotin receptor targeted glutathione-responsive photodynamic therapy-chemotherapy combined drug and preparation method and application thereof 徐州医科大学 2024-09-06 CN disclosed
US-12020872-B2 Stilbene and fused stilbene derivatives as solar cell dyes Ambient Photonics, Inc. (US) 2024-06-25 US disclosed
WO-2023228005-A1 COMPOUND AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2023-11-30 WO disclosed
EP-3621957-B1 FUSED STILBENE DERIVATIVES AS SOLAR CELL DYES AMBIENT PHOTONICS INC (US) 2023-08-23 EP disclosed
EP-3621957-B1 FUSED STILBENE DERIVATIVES AS SOLAR CELL DYES AMBIENT PHOTONICS INC (US) 2023-08-23 EP disclosed
CN-114989081-B Colorimetric probe and preparation method and application thereof 南华大学 2023-06-13 CN disclosed
US-11664171-B2 Stilbene and fused stilbene derivatives as solar cell dyes Ambient Photonics, Inc. (US) 2023-05-30 US disclosed
US-11664171-B2 Stilbene and fused stilbene derivatives as solar cell dyes Ambient Photonics, Inc. (US) 2023-05-30 US disclosed
US-11664171-B2 Stilbene and fused stilbene derivatives as solar cell dyes Ambient Photonics, Inc. (US) 2023-05-30 US disclosed
US-20080138728-A1 LATENT ELECTROSTATIC IMAGE BEARING MEMBER, AND IMAGE FORMING APPARATUS, IMAGE FORMING METHOD AND PROCESS CARTRIDGE USING THE SAME RICOH COMPANY, LTD. (JP) 2008-06-12 US disclosed
US-20080138728-A1 LATENT ELECTROSTATIC IMAGE BEARING MEMBER, AND IMAGE FORMING APPARATUS, IMAGE FORMING METHOD AND PROCESS CARTRIDGE USING THE SAME RICOH COMPANY, LTD. (JP) 2008-06-12 US disclosed
WO-2008055969-A1 NOVEL TRIPHENYLAMINE DERIVATIVES FOR USE AS FLUOROPHORES IN BIOLOGY, IN PARTICULAR FOR TWO-PHOTON MICROSCOPY COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2008-05-15 WO disclosed
US-6951952-B2 Dyes POLAROID CORPORATION (US) 2005-10-04 US disclosed
WO-2004078030-A2 RHODOL DERIVATIVES USEFUL AS IMAGE DYES POLAROID CORPORATION (US) 2004-09-16 WO disclosed
US-20040176617-A1 which exhibit a first color when in crystalline form and a second different color when in the liquid, amorphous form; for thermal imaging ZINK HOLDINGS LLC 2004-09-09 US disclosed
US-6627111-B2 Reduced pH sensitivity and enhanced stability to protonation; efficiency INTERNATIONAL BUSINESS MACHINES CORP. 2003-09-30 US disclosed
US-20020127428-A1 Organic light emitting displays and new fluorescent compounds INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2002-09-12 US disclosed
US-6440586-B1 SUSPENDED IN A POLYMER SUCH AS POLYVINYLCARBAZOLE FUJI PHOTO FILM CO., LTD. (JP) 2002-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020127428-A1 Organic light emitting displays and new fluorescent compounds TYR, MAP1LC3C, MAP1LC3A CA4 792/4885MTNR1A 1903/4885MTNR1B 1305/4885
US-20040176617-A1 which exhibit a first color when in crystalline form and a second different color when in the liquid, amorphous form; for thermal imaging IK, CRYAB, CRYAA CA4 79/4885MTNR1A 2547/4885MTNR1B 2352/4885
US-12020872-B2 Stilbene and fused stilbene derivatives as solar cell dyes FDFT1, SUN2, CDC73 CA4 2840/4885MTNR1A 2434/4885MTNR1B 2122/4885
US-11664171-B2 Stilbene and fused stilbene derivatives as solar cell dyes SUN2, FDFT1, SIK1 CA4 2878/4885MTNR1A 2986/4885MTNR1B 2792/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.