SCHEMBL8943790

SCHEMBL8943790

O=C(COc1ccccc1)Nc1ccccc1C(=O)O.[Zn]

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 3/20 0.79
ALDH1A1 P00352 4/20 0.74
MAPK10 P53779 3/20 0.74
TSHR P16473 2/20 0.74
HSD17B10 Q99714 1/20 0.74
MEN1 O00255 2/20 0.72
KMT2A Q03164 2/20 0.72
CASP3 P42574 1/20 0.72
SENP8 Q96LD8 1/20 0.72
SENP7 Q9BQF6 1/20 0.72
SENP6 Q9GZR1 1/20 0.72
NPC1 O15118 5/20 0.66
RAB9A P51151 4/20 0.66
KDM4E B2RXH2 4/20 0.64
POLB P06746 2/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
HIF1A Q16665 1/20 0.64
EPAS1 Q99814 1/20 0.64
TP53 P04637 1/20 0.58
RECQL P46063 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6032429 0.98 HCAR2 (0.81) HCAR2ALDH1A1MAPK10TSHRHSD17B10
SCHEMBL5696427 0.90 HCAR2 (0.78) HCAR2ALDH1A1MAPK10TSHRHSD17B10
SCHEMBL4912964 0.88 NPC1 (0.80) HCAR2ALDH1A1MAPK10TSHRHSD17B10
SCHEMBL18510324 0.88 NPC1 (0.80) HCAR2ALDH1A1MAPK10TSHRHSD17B10
SCHEMBL4914608 0.88 HCAR2 (0.76) HCAR2ALDH1A1MAPK10TSHRHSD17B10
SCHEMBL8689332 0.88 HCAR2 (1.00) HCAR2ALDH1A1MAPK10TSHRHSD17B10
SCHEMBL4915695 0.88 HCAR2 (0.76) HCAR2ALDH1A1MAPK10TSHRHSD17B10
SCHEMBL14449495 0.87 HCAR2 (0.77) HCAR2ALDH1A1MAPK10TSHRHSD17B10
SCHEMBL11597574 0.86 MAPK10 (0.72) HCAR2ALDH1A1MAPK10TSHRHSD17B10
SCHEMBL5696407 0.86 HCAR2 (0.76) HCAR2ALDH1A1MAPK10TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed