Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8088903 | 0.81 | ALOX15 (0.55) | CYP2D6CYP2C9CYP2C19TP53ALOX15 | |
| SCHEMBL9221138 | 0.79 | ACE2 (0.35) | CYP2D6CYP2C9CYP2C19ACE2ADRB2 | |
| SCHEMBL30288164 | 0.75 | AKR1C3 (0.49) | CYP2C9CYP2C19CYP1A2TSHRNFKB1 | |
| SCHEMBL223426 | 0.75 | ALOX15 (0.51) | CYP2D6CYP2C9CYP2C19TP53ALOX15 | |
| SCHEMBL30343443 | 0.72 | ALDH1A1 (0.53) | CYP2D6CYP2C9CYP2C19TP53ALOX15 | |
| SCHEMBL1596042 | 0.72 | ALDH1A1 (0.53) | CYP2D6CYP2C9CYP2C19TP53ALOX15 | |
| SCHEMBL6567193 | 0.71 | GAA (0.48) | CYP2D6CYP2C9CYP2C19TP53ALOX15 | |
| SCHEMBL3418296 | 0.71 | TP53 (0.35) | CYP2D6CYP2C9CYP2C19TP53ALOX15 | |
| SCHEMBL11455102 | 0.70 | TSHR (0.54) | CYP2D6CYP2C9CYP2C19TP53ALOX15 | |
| SCHEMBL6296180 | 0.70 | CYP2C9 (0.54) | CYP2D6CYP2C9CYP2C19TP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578665-A | HEAT AND OXIDATION RESISTANCE; PHOTOSTABILITY | CIBA-GEIGY CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |
| EP-0235077-B1 | CURABLE MIXTURES BASED ON DIGLYCIDYL COMPOUNDS AND METAL COMPLEXES | CIBA-GEIGY AG (CH) | 1990-09-19 | — | — | EP | disclosed |
| US-4716185-A | Curable mixtures based on diglycidyl compounds and metal complex compounds | CIBA-GEIGY CORPORATION (US) | 1987-12-29 | — | — | US | disclosed |
| EP-0235077-A2 | Curable mixtures based on diglycidyl compounds and metal complexes | CIBA-GEIGY AG (CH) | 1987-09-02 | — | — | EP | disclosed |