SCHEMBL8943882

SCHEMBL8943882

COc1ccc(N(c2ccccc2)c2ccc(C=Cc3ccc(N(c4ccccc4)c4ccc(OC)cc4)cc3)cc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.71
TRPM8 Q7Z2W7 3/20 0.58
RELA Q04206 4/20 0.55
NFE2L2 Q16236 3/20 0.53
CYP1A2 P05177 3/20 0.53
CYP1A1 P04798 3/20 0.53
CYP1B1 Q16678 3/20 0.53
ESR1 P03372 2/20 0.53
PTGS2 P35354 2/20 0.53
ABL1 P00519 1/20 0.53
TTR P02766 1/20 0.53
ABCB1 P08183 1/20 0.53
ALOX5 P09917 1/20 0.53
BCR P11274 1/20 0.53
CYP19A1 P11511 1/20 0.53
NQO2 P16083 1/20 0.53
TUBB4A P04350 1/20 0.53
TUBB P07437 1/20 0.53
TUBA3C P0DPH7 1/20 0.53
AHR P35869 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7873582 1.00 TRPA1 (0.71) TRPA1TRPM8RELANFE2L2CYP1A2
SCHEMBL8943877 1.00 TRPA1 (0.71) TRPA1TRPM8RELANFE2L2CYP1A2
SCHEMBL7821780 1.00 TRPA1 (0.71) TRPA1TRPM8RELANFE2L2CYP1A2
SCHEMBL6819752 1.00 TRPA1 (0.71) TRPA1TRPM8RELANFE2L2CYP1A2
SCHEMBL4402914 1.00 TRPA1 (0.71) TRPA1TRPM8RELANFE2L2CYP1A2
SCHEMBL6819748 1.00 TRPA1 (0.71) TRPA1TRPM8RELANFE2L2CYP1A2
SCHEMBL16492030 1.00 TRPA1 (0.71) TRPA1TRPM8RELANFE2L2CYP1A2
SCHEMBL5493474 0.98 TRPA1 (0.75) TRPA1TRPM8RELANFE2L2CYP1A2
SCHEMBL5493476 0.98 TRPA1 (0.75) TRPA1TRPM8RELANFE2L2CYP1A2
SCHEMBL5487747 0.96 TRPA1 (0.78) TRPA1TRPM8RELANFE2L2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed